Genome-wide SNP data unveils the globalization of domesticated pigs

B Yang, L Cui, M Perez-Enciso, A Traspov… - Genetics Selection …, 2017 - Springer
Background Pigs were domesticated independently in Eastern and Western Eurasia early
during the agricultural revolution, and have since been transported and traded across the …

[HTML][HTML] PPARs in atherosclerosis: The spatial and temporal features from mechanism to druggable targets

Y Zheng, M Shao, Y Zheng, W Sun, S Qin, Z Sun… - Journal of Advanced …, 2024 - Elsevier
Background Atherosclerosis is a chronic and complex disease caused by lipid disorder,
inflammation, and other factors. It is closely related to cardiovascular diseases, the chief …

Radiation-induced cardiovascular disease: an overlooked role for DNA methylation?

M Sallam, MA Benotmane, S Baatout, PJ Guns… - Epigenetics, 2022 - Taylor & Francis
Radiotherapy in cancer treatment involves the use of ionizing radiation for cancer cell killing.
Although radiotherapy has shown significant improvements on cancer recurrence and …

TBX20 regulates angiogenesis through the prokineticin 2–prokineticin receptor 1 pathway

S Meng, Q Gu, X Yang, J Lv, I Owusu, G Matrone… - Circulation, 2018 - Am Heart Assoc
Background: Angiogenesis is integral for embryogenesis, and targeting angiogenesis
improves the outcome of many pathological conditions in patients. TBX20 is a crucial …

Identification of novel hyper-or hypomethylated CpG sites and genes associated with atherosclerotic plaque using an epigenome-wide association study

Y Yamada, H Horibe, M Oguri… - International …, 2018 - spandidos-publications.com
DNA methylation is an important epigenetic modification that has been implicated in the
pathogenesis of atherosclerosis. Although previous studies have identified various CpG …

Chronological in vivo imaging reveals endothelial inflammation prior to neutrophils accumulation and lipid deposition in HCD-fed zebrafish

H Luo, Q Li, N Wu, Y Shen, W Liao, Y Yang, E Dong… - Atherosclerosis, 2019 - Elsevier
Background and aims Hyperlipidemia-induced atherosclerosis is the major cause of heart
attack and stroke in humans. However, pathological details and molecular mechanisms …

Longxuetongluo capsule inhibits atherosclerosis progression in high-fat diet-induced ApoE−/− mice by improving endothelial dysfunction

J Zheng, B Liu, Q Lun, X Gu, B Pan, Y Zhao, W Xiao… - Atherosclerosis, 2016 - Elsevier
Background and aims Chinese dragon's blood has been used to treat blood stasis for
thousands of years. Its total phenolic extract (Longxuetongluo capsule, LTC) is used for the …

[HTML][HTML] Cardiac shock wave therapy attenuates H9c2 myoblast apoptosis by activating the AKT signal pathway

W Yu, T Shen, B Liu, S Wang, J Li, D Dai… - Cellular Physiology and …, 2014 - karger.com
Background: Previous studies have demonstrated that Cardiac Shock Wave Therapy
(CSWT) improves myocardial perfusion and cardiac function in a porcine model of chronic …

Pinoresinol diglucoside alleviates oxLDL‐induced dysfunction in human umbilical vein endothelial cells

J Yao, Z Zou, X Wang, X Ji… - … Based Complementary and …, 2016 - Wiley Online Library
Atherosclerotic cardiovascular diseases are the leading causes of morbidity and mortality
worldwide. Deposition of oxidized low‐density lipoprotein (oxLDL) is one of the initiators and …

TBX20 contributes to balancing the differentiation of perivascular adipose-derived stem cells to vascular lineages and neointimal hyperplasia

Y Ji, Y Ma, J Shen, H Ni, Y Lu, Y Zhang… - Frontiers in Cell and …, 2021 - frontiersin.org
Background Perivascular adipose-derived stem cells (PVASCs) can contribute to vascular
remodeling, which are also capable of differentiating into multiple cell lineages. The present …