The large Trp gene family encodes transient receptor potential (TRP) proteins that form
novel cation-selective ion channels. In mammals, 28 Trp channel genes have been …

Arterial hypertension is a disease with a complex pathogenesis. Despite considerable
knowledge about this socially significant disease, the role of magnesium deficiency (MgD) …

The transient receptor potential channel TRPM7 is a master regulator of the organismal
balance of divalent cations that plays an essential role in embryonic development, immune …

Magnesium (Mg) is the second most abundant cation in mammalian cells, and it is essential
for numerous cellular processes including enzymatic reactions, ion channel functions …

Magnesium is the most abundant intracellular divalent cation and essential for maintaining
normal cellular physiology and metabolism, acting as a cofactor of numerous enzymes …

Magnesium reduces vascular smooth muscle cell (VSMC) calcification in vitro but the
mechanism has not been revealed so far. This work used only slightly increased magnesium …

Ca2+ influx through Ca2+ permeable ion channels is a key trigger and regulator of a diverse
set of cellular events, such as neurotransmitter release and muscle contraction. Ca2+ influx …

Members of the TRPM (“Melastatin”) family fall into the subclass of the TRP channels having
varying permeability to Ca2+ and Mg2+, with three members of the TRPM family being …

Magnesium (Mg) is an essential dietary element for humans involved in key biological
processes. A growing body of evidence from epidemiological studies, randomized controlled …

Transient receptor potential (TRP) channels contribute to the regulation of intracellular
calcium, which can promote cancer hallmarks in cases of dysregulation of gene transcription …