Factor H is an essential regulatory protein that plays a critical role in the homeostasis of the
complement system in plasma and in the protection of bystander host cells and tissues from …

The complement system constitutes an important component of the defence against foreign
organisms, functioning both in innate and adaptive immune systems. It is potentially harmful …

Complement factor H (FH) attenuates C3b molecules tethered by their thioester domains to
self surfaces and thereby protects host tissues. Factor H is a cofactor for initial C3b …

Human β 2‐glycoprotein I is a heavily glycosylated five‐domain plasma membrane‐
adhesion protein, which has been implicated in blood coagulation and clearance of …

The high affinity of human plasma β2‐glycoprotein I (β 2 GPI), also known as apolipoprotein‐
H (ApoH), for negatively charged phospholipids determines its implication in a variety of …

Complement factor H (FH) is an important regulator of the alternative complement pathway.
The Y402H polymorphism within the seventh short consensus repeat of FH was recently …

It has become standard practice to compare new amino-acid and nucleotide sequences with
existing ones in the rapidly growing sequence databases. This has led to the recurring …

A unique monoclonal Ig λ light chain dimer (protein LOI) was isolated from the serum and
urine of a patient with hypocomplementemic membranoproliferative glomerulonephritis. In …

Human complement factor H controls spontaneous activation of complement in plasma and
appears to play a role in distinguishing host cells from activators of the alternative pathway …

Complement factor H (fH) regulates activation of the alternative pathway of C, reducing the
amount of C3b deposited on sialic acid-rich surfaces. Heparin binding has been used as a …