Outlook for new CAR-based therapies with a focus on CAR NK cells: what lies beyond CAR-engineered T cells in the race against cancer

M Daher, K Rezvani - Cancer discovery, 2021 - AACR
Chimeric antigen receptor (CAR) engineering of T cells has revolutionized the field of
cellular therapy for the treatment of cancer. Despite this success, autologous CAR-T cells …

Adaptive NK cell therapy modulated by anti-PD-1 antibody in gastric cancer model

S Abdolahi, Z Ghazvinian… - Frontiers in …, 2021 - frontiersin.org
Recently, adaptive NK cell therapy has become a promising treatment but has limited
efficacy as a monotherapy. The identification of immune checkpoint inhibitor (ICI) molecules …

[PDF][PDF] Cell Therapy Using Anti-NKG2A Pretreated Natural Killer Cells in Patients with Hepatocellular Carcinoma

S Tavakoli, MS Salavati, S Abdolahi… - Advanced …, 2024 - apb.tbzmed.ac.ir
Purpose: The activities and functions of natural killer (NK) cells are regulated by a limited
repertoire of activating and inhibitory receptors. Thus, we provided a study of inhibition of the …