Pain is a subjective sensory experience that can, mostly, be reported but cannot be directly
measured or quantified. Nevertheless, a suite of biomarkers related to mechanisms, neural …

Alzheimer's disease is a progressive neurodegenerative disease that typically manifests
clinically as an isolated amnestic deficit that progresses to a characteristic dementia …

Medical imaging has enormous potential for early disease prediction, but is impeded by the
difficulty and expense of acquiring data sets before symptom onset. UK Biobank aims to …

This report discusses the public health impact of Alzheimer's disease (AD), including
incidence and prevalence, mortality rates, costs of care and the overall effect on caregivers …

This report discusses the public health impact of Alzheimer's disease (AD), including
incidence and prevalence, mortality rates, costs of care, and overall effect on caregivers and …

Is it possible to prevent atrophy of key brain regions related to cognitive decline and
Alzheimer's disease (AD)? One approach is to modify nongenetic risk factors, for instance by …

Functional and structural connectivity measures, as assessed by means of functional and
diffusion MRI, are emerging as potential intermediate biomarkers for Alzheimer disease (AD) …

Magnetic resonance imaging (MRI) has allowed the unprecedented capability to measure
the human brain in vivo. This technique has paved the way for longitudinal studies exploring …

Background Mild cognitive impairment (MCI) due to Alzheimer's disease is the symptomatic
predementia phase of Alzheimer's disease dementia, characterised by cognitive and …

Alzheimer's disease (AD) has traditionally been regarded as a disease of the gray matter
(GM). However, the advent of diffusion tensor imaging (DTI) has contributed to new …