Anticancer potential of ruthenium complexes has been widely investigated, but safety evaluation studies are still scarce. Despite of ruthenium-based anticancer agents are known …
ER Dos Santos, AE Graminha, MS Schultz… - Journal of inorganic …, 2018 - Elsevier
Thirteen new ruthenium amino acid complexes were synthesized and characterized. They were obtained by the reaction of α-amino acids (AA) with [RuCl 2 (PP)(NN)], where PP= 1, 4 …
This study performed in vitro and in vivo biological assays of the ruthenium (II) compound ct- [RuCl (CO)(dppb)(bipy)] PF 6 (where, dppb= 1, 4-bis (diphenylphosphine) butane and bipy …
Non-small cell lung cancer (NSCLC) is the most common cancer worldwide, which is related with poor prognosis and resistance to chemotherapy. Notably, ruthenium-based complexes …
IH de Sousa, VNS Campos, AAM Vale… - Toxicology in Vitro, 2020 - Elsevier
Ruthenium complexes are being considered as novel chemotherapeutic alternatives for cancer treatment. In our study, we assessed the antitumoral activities of novel ruthenium …
F Sabbagh, II Muhamad, Z Nazari, P Mobini… - Materials Today …, 2018 - Elsevier
In the current research, based on the investigation of the drug-loaded hydrogels, the maximum content of acyclovir loading in polymer consequently relates to the pH at which the …
Peritoneal carcinomatosis is considered as a potentially lethal clinical condition, and the therapeutic options are limited. The antitumor effectiveness of the [Ru (l-Met)(bipy)(dppb)] …
TM Teixeira, IG Arraes, DC Abreu, KM Oliveira… - European Journal of …, 2021 - Elsevier
The number of cancer cases continues to increase worldwide, and unfortunately the main systemic treatments available have numerous of side effects. Ruthenium complexes have …