Alzheimer's disease (AD) is the most common cause of dementia, accounting for more than
50 million patients worldwide. Current evidence suggests the exact mechanism behind this …

Abstract Behavioral and Psychological Symptoms of Dementia (BPSD), present in almost
90% of patients with Alzheimer's Disease (AD), cause extensive impairment leading to …

Abstract In mammalians, serotonin (5-HT) has critical roles in the central nervous system
(CNS), including mood stability, pain tolerance, or sleep patterns. However, the vast majority …

HT7 receptors (5-HT7R) are the most recently identified among the family of serotonin
receptors. Their role in health and disease, particularly as mediators of, and druggable …

Biomedical application of quercetin (QT) as an effective flavonoid has limitations due to its
low bioavailability. Superparamagnetic iron oxide nanoparticle (SPION) is a novel drug …

Given the failure to develop disease-modifying therapies for Alzheimer's disease (AD),
strategies aiming at preventing or delaying the onset of the disease are being prioritized …

Alzheimer's disease (AD) is a progressive neurodegenerative disease. The accumulation of
amyloid-β (Aβ) plaques and tau neurofibrillary tangles are the key players responsible for …

Although a number of mood-stabilising atypical antipsychotics and antidepressants
modulate serotonin type 7 receptor (5-HT7), the detailed contributions of 5-HT7 function to …

Alpinia oxyphylla Miq.(ie, A. oxyphylla), a traditional Chinese medicine, can exert
neuroprotective effects in ameliorating mild cognitive impairment and improving the …

Rationale Alzheimer's disease (AD) is the most common form of dementia characterized by
a progressive decline in cognitive function. The serotonergic system via the 5-HT1A receptor …