[HTML][HTML] Multiple roles for basement membrane proteins in cancer progression and EMT

S Banerjee, WC Lo, P Majumder, D Roy… - European Journal of …, 2022 - Elsevier
Metastasis or the progression of malignancy poses a major challenge in cancer therapy and
is the principal reason for increased mortality. The epithelial-mesenchymal transition (EMT) …

SWATH‐MS as a tool for biomarker discovery: From basic research to clinical applications

SI Anjo, C Santa, B Manadas - Proteomics, 2017 - Wiley Online Library
In the era of quantitative proteomics, where mass spectrometry plays a pivotal role, in
particular associated with the use of data‐independent acquisition, it is time to perform an …

Advances in proteomic techniques for cytokine analysis: focus on melanoma research

H Kupcova Skalnikova, J Cizkova, J Cervenka… - International journal of …, 2017 - mdpi.com
Melanoma is a skin cancer with permanently increasing incidence and resistance to
therapies in advanced stages. Reports of spontaneous regression and tumour infiltration …

Upregulation of LAMB1 via ERK/c-Jun axis promotes gastric cancer growth and motility

H Lee, WJ Kim, HG Kang, JH Jang, IJ Choi… - International journal of …, 2021 - mdpi.com
Gastric cancer is the fifth most common cancer worldwide with a poor survival rate.
Therefore, it is important to identify predictive and prognostic biomarkers of gastric cancer …

Protein glycosylation in gastric and colorectal cancers: Toward cancer detection and targeted therapeutics

JA Ferreira, A Magalhaes, J Gomes, A Peixoto… - Cancer letters, 2017 - Elsevier
Glycosylation is the most frequent and structurally complex posttranslational modification in
cell-surface and secreted proteins. Glycans are major orchestrators of biological processes …

Extracellular matrix biomarkers in colorectal cancer

MS Kim, SE Ha, M Wu, H Zogg, CF Ronkon… - International journal of …, 2021 - mdpi.com
The cellular microenvironment composition and changes therein play an extremely
important role in cancer development. Changes in the extracellular matrix (ECM), which …

Human mast cells promote colon cancer growth via bidirectional crosstalk: studies in 2D and 3D coculture models

Y Yu, B Blokhuis, Y Derks, S Kumari, J Garssen… - …, 2018 - Taylor & Francis
Chronic inflammation drives the development of colorectal cancer (CRC), where tumor-
infiltrating immune cells interact with cancer cells in a dynamic crosstalk. Mast cells (MC) …

Characterizing disease-associated changes in post-translational modifications by mass spectrometry

C Thygesen, I Boll, B Finsen, M Modzel… - Expert review of …, 2018 - Taylor & Francis
Introduction: Exploring post-translational modifications (PTMs) with the use of mass
spectrometry (PTMomics) is a rapidly developing area, with methods for discovery …

Probing the colorectal cancer proteome for biomarkers: Current status and perspectives

PY Lee, SF Chin, TY Low, R Jamal - Journal of proteomics, 2018 - Elsevier
Colorectal cancer (CRC) is one of the most prevalent malignancies worldwide. Biomarkers
that can facilitate better clinical management of CRC are in high demand to improve patient …

Biomarker discovery by proteomics‐based approaches for early detection and personalized medicine in colorectal cancer

C Corbo, A Cevenini, F Salvatore - PROTEOMICS–Clinical …, 2017 - Wiley Online Library
About one million people per year develop colorectal cancer (CRC) and approximately half
of them die. The extent of the disease (ie local invasion at the time of diagnosis) is a key …