Milk thistle in liver diseases: past, present, future

L Abenavoli, R Capasso, N Milic… - Phytotherapy …, 2010 - Wiley Online Library
Silybum marianum or milk thistle (MT) is the most well‐researched plant in the treatment of
liver disease. The active complex of MT is a lipophilic extract from the seeds of the plant and …

The use of silymarin in the treatment of liver diseases

R Saller, R Meier, R Brignoli - Drugs, 2001 - Springer
The high prevalence of liver diseases such as chronic hepatitis and cirrhosis underscores
the need for efficient and cost-effective treatments. The potential benefit of silymarin …

Hepatoprotective herbal drug, silymarin from experimental pharmacology to clinical medicine

SC Pradhan, C Girish - Indian journal of medical research, 2006 - journals.lww.com
Silymarin, a flavonolignan from′ milk thistle′(Silybum marianum) plant is used almost
exclusively for hepatoprotection and amounts to 180 million US dollars business in Germany …

Comparison of antioxidant activities of onion and garlic extracts by inhibition of lipid peroxidation and radical scavenging activity

AM Nuutila, R Puupponen-Pimiä, M Aarni… - Food chemistry, 2003 - Elsevier
The antioxidant activities of the methanol extracts of selected varieties and parts of garlic
and onion were determined by two methods: inhibition of lipid peroxidation induced by tert …

[PDF][PDF] A review of plants used in the treatment of liver disease: part 1

ND Scott Luper - Alternative medicine review, 1998 - anaturalhealingcenter.com
Botanicals have been used traditionally by herbalists and indigenous healers worldwide for
the prevention and treatment of liver disease. Clinical research in this century has confirmed …

Pharmacology of silymarin

F Fraschini, G Demartini, D Esposti - Clinical drug investigation, 2002 - Springer
The flavonoid silymarin and one of its structural components, silibinin, are substances with
documented hepatoprotective properties. Their mechanisms of action are still poorly …

Silymarin: a review of its clinical properties in the management of hepatic disorders

K Wellington, B Jarvis - BioDrugs, 2001 - Springer
The mechanisms of action of silymarin involve different biochemical events, such as the
stimulation of the synthetic rate of ribosomal RNA (rRNA) species through stimulation of …

Hepatoprotective activity of thymoquinone in isolated rat hepatocytes

MH Daba, MS Abdel-Rahman - Toxicology letters, 1998 - Elsevier
Thymoquinone, the active constituent of Nigella sativa, was tested in isolated rat
hepatocytes as a hepatoprotective agent against tert-butyl hydroperoxide (TBHP) toxicity …

Silymarin prevents acetaminophen-induced hepatotoxicity in mice

Z Papackova, M Heczkova, H Dankova, E Sticova… - PloS one, 2018 - journals.plos.org
Acetaminophen or paracetamol (APAP) overdose is a common cause of liver injury.
Silymarin (SLM) is a hepatoprotective agent widely used for treating liver injury of different …

Natural polyphenols in metabolic syndrome: protective mechanisms and clinical applications

S Zhang, M Xu, W Zhang, C Liu, S Chen - International journal of …, 2021 - mdpi.com
Metabolic syndrome (MetS) is a chronic disease, including abdominal obesity, dyslipidemia,
hyperglycemia, and hypertension. It should be noted that the occurrence of MetS is closely …