JL Giner, H Zhao, DH Beach, EJ Parish… - Journal of lipid …, 2002 - ASBMB
Pneumocystis causes a type of pneumonia in immunodeficient mammals, such as AIDS patients. Mammals cannot alkylate the C-24 position of the sterol side chain, nor can they …
Pneumocystis carinii is the paradigm of opportunistic infections in immunocompromised mammals. Prior to the acquired immunodeficiency syndrome (AIDS) pandemic and the use …
ES Kaneshiro, Z Amit, J Chandra… - Clinical Diagnostic …, 1999 - Am Soc Microbiol
The opportunistic pathogen Pneumocystis carinii causes pneumonia (P. carinii pneumonia, or PCP) in immunocompromised individuals such as AIDS patients. Rat-derived P. carinii …
Pneumocystis can transiently colonize healthy individuals without causing adverse symptoms, and most people test positive for exposure to this organism early in life. However …
JL GINER, H Zhao, Z Amit… - Journal of Eukaryotic …, 2004 - Wiley Online Library
Several drugs that interact with membrane sterols or inhibit their syntheses are effective in clearing a number of fungal infections. The AIDS‐associated lung infection caused by …
Pneumocystis, an opportunistic fungal protist, causes a type of pneumonia in immunocompromised individuals such as AIDS patients. Rat-derived P. carinii and human …