This review summarizes our current understanding of catechol-o-methyltransferase (COMT) and how it relates to brain function and schizophrenia. We begin by considering the COMT …
MDG Dominguez, M Wichers, R Lieb… - Schizophrenia …, 2011 - academic.oup.com
This study examined the hypothesis that developmental expression of psychometric risk in the form of subclinical psychotic experiences in the general population is usually transitory …
The antisaccade task is a measure of volitional control of behavior sensitive to fronto‐striatal dysfunction. Here we outline important issues concerning antisaccade methodology …
A Raine - Annu. Rev. Clin. Psychol., 2006 - annualreviews.org
Schizotypal personality research holds the promise of critically important insights into the etiology and ultimate prevention of schizophrenia. This article provides a critical overview of …
This compelling book argues that all people with schizophrenia share a personality organization known as schizotypy. Presented is a novel framework for understanding …
The idea that some phenotypes bear a closer relationship to the biological processes that give rise to psychiatric illness than diagnostic categories has attracted considerable interest …
BACKGROUND: Cognitive endophenotypes may further our understanding of the genetic basis of psychiatric disorders, and the catechol-O-methyltransferase (COMT) gene is a …
The important contribution of genetic factors to the development of cognition and intelligence is widely acknowledged, but identification of these genes has proven to be difficult. Given a …
BackgroundIt has been suggested that some psychotic symptoms reflect 'aberrant salience', related to dysfunctional reward learning. To test this hypothesis we investigated whether …