The formation and maintenance of tissue integrity requires complex, coordinated activities
by thousands of genes and their encoded products. Until recently, transcript levels could …

Fluorescence provides a mechanism for achieving contrast in biological imaging that
enables investigations of molecular structure, dynamics, and function at high spatial and …

Newly developed scientific complementary metal-oxide semiconductor (sCMOS) cameras
have the potential to dramatically accelerate data acquisition, enlarge the field of view and …

The rapid development of scientific CMOS (sCMOS) technology has greatly advanced
optical microscopy for biomedical research with superior sensitivity, resolution, field-of-view …

The integration of synthetic and cell-free biology has made tremendous strides towards
creating artificial cellular nanosystems using concepts from solution-based chemistry, where …

Single-molecule fluorescence microscopy is uniquely suited for detecting transient
molecular recognition events, yet achieving the time resolution and statistics needed to …

Highlights•The potential impact of multi-color single-molecule FRET imaging.•Key
requirement: ultra-stable fluorophores spanning the visible spectrum.•Intramolecularly …

Single-molecule fluorescence techniques are ideally suited to provide information about the
structure-function-dynamics relationship of a biomolecule as static and dynamic …

Dry eye disease (DED) affects millions of individuals in the United States and worldwide,
and the incidence is increasing with an aging population. There is widespread agreement …

Occurrence and distribution of microplastics in different ecosystems have recently become
subjects of numerous studies. However, to date the research has focused mainly on marine …