[HTML][HTML] Role of miRNA and lncRNAs in organ fibrosis and aging

S Ghafouri-Fard, A Abak, SF Talebi, H Shoorei… - Biomedicine & …, 2021 - Elsevier
Fibrosis is the endpoint of pathological remodeling. This process contributes to the
pathogenesis of several chronic disorders and aging-associated organ damage. Different …

NORAD, a critical long non-coding RNA in human cancers

N Soghli, T Yousefi, M Abolghasemi, D Qujeq - Life Sciences, 2021 - Elsevier
The incidence of cancer is growing worldwide, and it is becoming the most common cause
of death. Long non-coding RNAs (lncRNAs) are a group of RNA transcripts with a length …

Induction of lncRNA NORAD accounts for hypoxia-induced chemoresistance and vasculogenic mimicry in colorectal cancer by sponging the miR-495-3p/hypoxia …

L Zhang, H Wu, Y Zhang, X Xiao, F Chu, L Zhang - Bioengineered, 2022 - Taylor & Francis
Hypoxic microenvironment represents the hallmark of solid tumors including colorectal
cancer (CRC) and facilitates angiogenesis and chemoresistance, leading to poor prognosis …

Long non-coding RNA signature in colorectal cancer: research progression and clinical application

Y Wu, X Xu - Cancer Cell International, 2023 - Springer
Colorectal cancer is one of the top-ranked human malignancies. The development and
progression of colorectal cancer are associated with aberrant expression of multiple coding …

Long non-coding RNA MEG3 alleviated ulcerative colitis through upregulating miR-98-5p-sponged IL-10

Y Wang, N Wang, L Cui, Y Li, Z Cao, X Wu, Q Wang… - Inflammation, 2021 - Springer
Ulcerative colitis (UC) is a refractory chronic colitis disease with the particularly complex
cause. Recently, long noncoding RNAs (lncRNAs) have been reported to be related to the …

Long noncoding RNA LINC00657 induced by SP1 contributes to the non‐small cell lung cancer progression through targeting miR‐26b‐5p/COMMD8 axis

R Zhang, Z Niu, H Pei, Z Peng - Journal of cellular physiology, 2020 - Wiley Online Library
Non‐small‐cell lung cancer (NSCLC) is a kind of lung cancer with high incidence and poor
outcomes all over the world. Studies have validated that the upregulation of long noncoding …

[PDF][PDF] The emerging role of lncRNA MEG3 and MEG3 rs7158663 in hepatocellular carcinoma.

SR Mohammed, OG Shaker… - European Review for …, 2022 - europeanreview.org
OBJECTIVE: Hepatocellular carcinoma (HCC) is the most common primary liver malignancy
in Egypt. Genetic and environmental factors play a role in its development. This study …

New circulating circular RNAs with diagnostic and prognostic potential in advanced colorectal cancer

M Radanova, G Mihaylova, O Tasinov… - International Journal of …, 2021 - mdpi.com
Circular RNAs (circRNAs) are a group of special endogenous long non-coding RNAs which
are highly stable in the circulation, and, thus, more suitable as new biomarkers of colorectal …

HNRNPH1-stabilized LINC00662 promotes ovarian cancer progression by activating the GRP78/p38 pathway

Y Wu, Q Guo, X Ju, Z Hu, L Xia, Y Deng, P Zhao… - Oncogene, 2021 - nature.com
Numerous studies suggest an important role for copy number alterations (CNAs) in cancer
progression. However, CNAs of long intergenic noncoding RNAs (lincRNAs) in ovarian …

Association analyses of a genetic variant in long non-coding RNA MEG3 with breast cancer susceptibility and serum MEG3 expression level in the Egyptian …

MA Ali, OG Shaker, M Alazrak… - Cancer …, 2020 - content.iospress.com
BACKGROUND: LncRNA MEG3 rs7158663 has been shown to confer cancer susceptibility,
maybe through altering its gene expression level. OBJECTIVE: We aimed to weigh the effect …