Hypoxia development in tumor is closely associated with its increased aggressiveness and
strong resistance to therapy, leading to the poor prognosis in several cancer types …

The discovery of new photosensitizer drugs with long wavelength Uv–vis absorption, high
efficiency and low side-effects is still a challenge in photodynamic therapy. Here a series of …

The administration of 5-aminolevulinic acid (ALA) to generate enhanced intracellular levels
of endogenous porphyrins is currently one of the most important approaches for …

Bio-derived furans such as 2-furfural (furfural), 5-hydroxymethyl-2-furfural (5-HMF) and 5-
methyl-2-furfural (5-MF) were successfully transformed to a ketoacid, levulinic acid (LA), and …

Aminolevulinic acid (ALA) is a FDA-approved photodynamic therapy (PDT) precursor of
protoporphyrin IX (PpIX) used for treating various cancers. However, the internalization of …

Efficient tandem catalytic transformations of bioderived furans, such as furfural, 5‐
hydroxymethylfurfural (5‐HMF), and 5‐methylfurfural (5‐MF), to levulinic acid (LA) and …

Photodynamic therapy (PDT) is a promising treatment strategy for malignant and
nonmalignant lesions. 5-Aminolaevulinic acid (ALA) is used as a precursor of the …

Photodynamic therapy (PDT) is a novel therapy that achieves therapeutic effects by exciting
photosensitizers accumulated in tumour tissues with specific wavelengths of light. Among …

Purpose As a precursor of the potent photosensitizer protoporphyrin IX (PpIX), 5-
aminolevulinic acid (5-ALA), was conjugated onto cationic gold nanoparticles (GNPs) to …

Aminolevulinic acid (5-ALA) and its two ester derivatives (5-ALA-OMe and 5-ALA-OHex)
have been approved for photodiagnosis and photodynamic therapy (PDT) of tumors in the …