Acute right ventricular (RV) failure is a complex clinical syndrome that results from many
causes. Research efforts have disproportionately focused on the failing left ventricle, but …

Pulmonary arterial hypertension (PAH) is a right heart failure syndrome. In early-stage PAH,
the right ventricle tends to remain adapted to afterload with increased contractility and little …

Pulmonary arterial hypertension (PAH) is an obstructive pulmonary vasculopathy,
characterized by excess proliferation, apoptosis resistance, inflammation, fibrosis, and …

Pulmonary hypertension is a progressive and often fatal cardiopulmonary condition
characterised by increased pulmonary arterial pressure, structural changes in the pulmonary …

BACKGROUND: Even after years of stable response to therapy, patients with idiopathic
pulmonary arterial hypertension (IPAH) may show an unexpected clinical deterioration due …

Breviscapine is a crude extract of several flavonoids of Erigeron breviscapus (Vant.) Hand.-
Mazz., containing more than 85% of scutellarin, which has been traditionally used in China …

Right ventricular (RV) function is a major determinant of the symptomatology and outcome in
pulmonary hypertension. The normal RV is a thin-walled flow generator able to …

Rationale: Right ventricular (RV) failure is a major cause of morbidity and mortality in
pulmonary hypertension, but its mechanism remains unknown. Myocyte enhancer factor 2 …

In pulmonary arterial hypertension (PAH), upfront combination therapy is associated with
better clinical outcomes and a greater reduction in N-terminal pro-brain natriuretic peptide …

Pulmonary hypertension (PH) is characterized by elevated pulmonary arterial pressure,
which leads to right ventricular (RV) hypertrophy and failure. The pathophysiological …