Nanozymes for regenerative medicine

X Mou, Q Wu, Z Zhang, Y Liu, J Zhang, C Zhang… - Small …, 2022 - Wiley Online Library
Nanozymes refer to nanomaterials that catalyze enzyme substrates into products under
relevant physiological conditions following enzyme kinetics. Compared to natural enzymes …

Metal oxide nanoparticles: review of synthesis, characterization and biological effects

AM Negrescu, MS Killian, SNV Raghu… - Journal of Functional …, 2022 - mdpi.com
In the last few years, the progress made in the field of nanotechnology has allowed
researchers to develop and synthesize nanosized materials with unique physicochemical …

A novel approach for the prevention of ionizing radiation-induced bone loss using a designer multifunctional cerium oxide nanozyme

F Wei, CJ Neal, TS Sakthivel, Y Fu, M Omer… - Bioactive materials, 2023 - Elsevier
The disability, mortality and costs due to ionizing radiation (IR)-induced osteoporotic bone
fractures are substantial and no effective therapy exists. Ionizing radiation increases cellular …

Sequential therapy for bone regeneration by cerium oxide-reinforced 3D-printed bioactive glass scaffolds

M Zhang, X Zhai, T Ma, Y Huang, M Jin, H Yang, H Fu… - ACS …, 2023 - ACS Publications
Rational design of multifunctional biomaterials with customized architecture and on demand
bioactivity is of great significance for bone tissue engineering (BTE) in modern society …

Nanomaterials in bone regeneration

V Babuska, PB Kasi, P Chocholata, L Wiesnerova… - Applied Sciences, 2022 - mdpi.com
Nanomaterials are promising in the development of innovative therapeutic options that
include tissue and organ replacement, as well as bone repair and regeneration. The …

A Brief Review on Cerium Oxide (CeO2NPs)-Based Scaffolds: Recent Advances in Wound Healing Applications

I Allu, A Kumar Sahi, P Kumari, K Sakhile… - Micromachines, 2023 - mdpi.com
The process of wound healing is complex and involves the interaction of multiple cells, each
with a distinct role in the inflammatory, proliferative, and remodeling phases. Chronic …

Inorganic nanoparticles in bone healing applications

AC Burdușel, O Gherasim, E Andronescu… - Pharmaceutics, 2022 - mdpi.com
Modern biomedicine aims to develop integrated solutions that use medical,
biotechnological, materials science, and engineering concepts to create functional …

Nanomaterial-based reactive oxygen species scavengers for osteoarthritis therapy

S Zhang, L Wang, Y Kang, J Wu, Z Zhang - Acta Biomaterialia, 2023 - Elsevier
Reactive oxygen species (ROS) play distinct but important roles in physiological and
pathophysiological processes. Recent studies on osteoarthritis (OA) have suggested that …

Construction of tellurium-doped mesoporous bioactive glass nanoparticles for bone cancer therapy by promoting ROS-mediated apoptosis and antibacterial activity

Y Zhang, M Hu, W Zhang, X Zhang - Journal of Colloid and Interface …, 2022 - Elsevier
The commonly used treatment methods for bone cancer include chemotherapy, surgery and
radiotherapy, but there are disadvantages such as nonspecific distribution, high toxicity of …

Multifunctional scaffolds for bone repair following age-related biological decline: Promising prospects for smart biomaterial-driven technologies

JD Schwartzman, M McCall, Y Ghattas… - Biomaterials, 2024 - Elsevier
The repair of large bone defects due to trauma, disease, and infection can be exceptionally
challenging in the elderly. Despite best clinical practice, bone regeneration within …