[HTML][HTML] Understanding psychiatric disorder by capturing ecologically relevant features of learning and decision-making
J Scholl, M Klein-Flügge - Behavioural brain research, 2018 - Elsevier
Recent research in cognitive neuroscience has begun to uncover the processes underlying
increasingly complex voluntary behaviours, including learning and decision-making. Partly …
increasingly complex voluntary behaviours, including learning and decision-making. Partly …
Activation and disruption of a neural mechanism for novel choice in monkeys
Neural mechanisms that mediate the ability to make value-guided decisions have received
substantial attention in humans and animals,,,,–. Experiments in animals typically involve …
substantial attention in humans and animals,,,,–. Experiments in animals typically involve …
The good, the bad, and the irrelevant: neural mechanisms of learning real and hypothetical rewards and effort
Natural environments are complex, and a single choice can lead to multiple outcomes.
Agents should learn which outcomes are due to their choices and therefore relevant for …
Agents should learn which outcomes are due to their choices and therefore relevant for …
Advances in pharmacotherapy development: human clinical studies
RZ Litten, DE Falk, ML Ryan, J Fertig… - The Neuropharmacology of …, 2018 - Springer
For more than 25 years, researchers have made advances in developing medications to
treat alcohol use disorder (AUD), highlighted by the US Food and Drug Administration's …
treat alcohol use disorder (AUD), highlighted by the US Food and Drug Administration's …
Augmenting NMDA receptor signaling boosts experience-dependent neuroplasticity in the adult human brain
Experience-dependent plasticity is a fundamental property of the brain. It is critical for
everyday function, is impaired in a range of neurological and psychiatric disorders, and …
everyday function, is impaired in a range of neurological and psychiatric disorders, and …
Beyond negative valence: 2-week administration of a serotonergic antidepressant enhances both reward and effort learning signals
To make good decisions, humans need to learn about and integrate different sources of
appetitive and aversive information. While serotonin has been linked to value-based …
appetitive and aversive information. While serotonin has been linked to value-based …
Consistent patterns of distractor effects during decision making
The value of a third potential option or distractor can alter the way in which decisions are
made between two other options. Two hypotheses have received empirical support: that a …
made between two other options. Two hypotheses have received empirical support: that a …
Excitation and inhibition in anterior cingulate predict use of past experiences
Dorsal anterior cingulate cortex (dACC) mediates updating and maintenance of cognitive
models of the world used to drive adaptive reward-guided behavior. We investigated the …
models of the world used to drive adaptive reward-guided behavior. We investigated the …
Cognitive and emotional empathy after stimulation of brain mineralocorticoid and NMDA receptors in patients with major depression and healthy controls
J Nowacki, K Wingenfeld, M Kaczmarczyk… - …, 2020 - nature.com
Mineralocorticoid receptors (MR) are predominantly expressed in the hippocampus and
prefrontal cortex. Both brain areas are associated with social cognition, which includes …
prefrontal cortex. Both brain areas are associated with social cognition, which includes …
Distractor effects in decision making are related to the individual's style of integrating choice attributes
Humans make irrational decisions in the presence of irrelevant distractor options. There is
little consensus on whether decision making is facilitated or impaired by the presence of a …
little consensus on whether decision making is facilitated or impaired by the presence of a …