2021 DORIS definition of remission in SLE: final recommendations from an international task force

RF van Vollenhoven, G Bertsias, A Doria… - Lupus science & …, 2021 - lupus.bmj.com
Objective To achieve consensus on a definition of remission in SLE (DORIS). Background
Remission is the stated goal for both patient and caregiver, but consensus on a definition of …

Lupus low disease activity state and remission and risk of mortality in patients with systemic lupus erythematosus: a prospective, multinational, longitudinal cohort …

R Kandane-Rathnayake, V Golder… - The Lancet …, 2022 - thelancet.com
Background Treat-to-target goals for patients with systemic lupus erythematosus (SLE) have
been validated to protect against organ damage and to improve quality of life. We aimed to …

'Not at target': prevalence and consequences of inadequate disease control in systemic lupus erythematosus—a multinational observational cohort study

R Kandane-Rathnayake, W Louthrenoo, A Hoi… - Arthritis Research & …, 2022 - Springer
Background The unmet need in systemic lupus erythematosus (SLE) with the current
standard of care is widely recognised, but few studies have quantified this. The recent …

Impact of low disease activity, remission, and complete remission on flares following tapering of corticosteroids and immunosuppressive therapy in patients with …

J Cho, L Shen, M Huq… - The Lancet …, 2023 - thelancet.com
Background Targets of treatment for systemic lupus erythematosus (SLE) include the Lupus
Low Disease Activity State (LLDAS), remission, and complete remission. Whether treatment …

Factors associated with damage accrual in patients with systemic lupus erythematosus with no clinical or serological disease activity: a multicentre cohort study

D Apostolopoulos, R Kandane-Rathnayake… - The Lancet …, 2020 - thelancet.com
Background Evaluating the contribution of glucocorticoid use to organ damage in systemic
lupus erythematosus is confounded by glucocorticoid use in active disease. We sought to …

Lupus education for physicians and patients in a resource-limited setting

SV Navarra, LD Zamora, MTM Collante - Clinical rheumatology, 2020 - Springer
Systemic lupus erythematosus (SLE) is a chronic autoimmune disease with a wide range of
manifestations and potential to affect several organ systems. Complications arise from both …

Independent associations of lymphopenia and neutropenia in patients with systemic lupus erythematosus: a longitudinal, multinational study

R Kandane-Rathnayake, W Louthrenoo… - …, 2021 - academic.oup.com
Objective The prevalence and associations of leucopenia in SLE remain incompletely
understood. We evaluated associations of disease activity and medication use with …

Indian SLE Inception cohort for Research (INSPIRE): the design of a multi-institutional cohort

V Shobha, A Aggarwal, L Rajasekhar, A Jain… - Rheumatology …, 2021 - Springer
Systemic lupus erythematosus (SLE) cohorts across the world have allowed better
understanding of SLE, including its bimodal mortality, and the impact of social factors and …

SMART-SLE: serology monitoring and repeat testing in systemic lupus erythematosus—an analysis of anti-double-stranded DNA monitoring

AL Yeo, R Kandane-Rathnayake, R Koelmeyer… - …, 2024 - academic.oup.com
Objective Disease activity monitoring in SLE includes serial measurement of anti-double
stranded-DNA (dsDNA) antibodies, but in patients who are persistently anti-dsDNA positive …

Comparison of attainment and protective effects of lupus low disease activity state in patients with newly diagnosed versus established systemic lupus erythematosus

V Golder, R Kandane-Rathnayake… - The Journal of …, 2024 - jrheum.org
Objective To assess whether Lupus Low Disease Activity State (LLDAS) attainment is
associated with favorable outcomes in patients with recent onset systemic lupus …