Immune responses in mildly versus critically ill COVID-19 patients

H Nasrollahi, AG Talepoor, Z Saleh… - Frontiers in …, 2023 - frontiersin.org
The current coronavirus pandemic (COVID-19), caused by SARS-CoV-2, has had
devastating effects on the global health and economic system. The cellular and molecular …

Innate and adaptive immunity during SARS-CoV-2 infection: biomolecular cellular markers and mechanisms

B Brown, V Ojha, I Fricke, SA Al-Sheboul, C Imarogbe… - Vaccines, 2023 - mdpi.com
The coronavirus 2019 (COVID-19) pandemic was caused by a positive sense single-
stranded RNA (ssRNA) severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) …

Tissue injury and leukocyte changes in post-acute sequelae of SARS-CoV-2: review of 2833 post-acute patient outcomes per immune dysregulation and microbial …

MS Islam, Z Wang, M Abdel-Mohsen… - Journal of Leukocyte …, 2023 - academic.oup.com
A significant number of persons with coronavirus disease 2019 (COVID-19) experience
persistent, recurrent, or new symptoms several months after the acute stage of severe acute …

Immune cells in subretinal wound healing and fibrosis

M Szczepan, M Llorián-Salvador, M Chen… - Frontiers in Cellular …, 2022 - frontiersin.org
The subretinal space is devoid of any immune cells under normal conditions and is an
immune privileged site. When photoreceptors and/or retinal pigment epithelial cells suffer …

Restoration of dendritic cell homeostasis and Type I/Type III interferon levels in convalescent COVID-19 individuals

A Rajamanickam, NP Kumar, AN Pandiaraj… - BMC immunology, 2022 - Springer
Background Plasmacytoid and myeloid dendritic cells play a vital role in the protection
against viral infections. In COVID-19, there is an impairment of dendritic cell (DC) function …

A multiscale mechanistic model of human dendritic cells for in-silico investigation of immune responses and novel therapeutics discovery

SS Aghamiri, BL Puniya, R Amin, T Helikar - Frontiers in Immunology, 2023 - frontiersin.org
Dendritic cells (DCs) are professional antigen-presenting cells (APCs) with the unique ability
to mediate inflammatory responses of the immune system. Given the critical role of DCs in …

Developing dendritic cell for SARS-CoV-2 vaccine: Breakthrough in the pandemic

J Jonny, TA Putranto, R Irfon, EC Sitepu - Frontiers in immunology, 2022 - frontiersin.org
Finding a vaccine that can last a long time and effective against viruses with high mutation
rates such as SARS-CoV-2 is still a challenge today. The various vaccines that have been …

Mechanisms of cardiovascular system injury induced by COVID-19 in elderly patients with cardiovascular history

Y Yang, M Yan - Frontiers in Cardiovascular Medicine, 2022 - frontiersin.org
The coronavirus disease-2019 (COVID-19) pandemic, caused by severe acute respiratory
syndrome coronavirus (SARS-CoV-2), represents a great threat to healthcare and …

Advances in understanding epigenetic impacts on dendritic cell regulation and function

Z Verlander, A Cummings, HM Brown… - Clinical and …, 2022 - Wiley Online Library
Dendritic cells (DCs) are the only cells empowered with inducing primary immune response
among resting naïve T lymphocytes, hence it is crucial to understand the regulation and …

Human Immune Responses to Sars-Cov-2 and Influenza a Virus Infection: From Myeloid-Derived Suppressor Cells and t cell Functions to Antibody Responses

M Yu - 2022 - search.proquest.com
Acute respiratory viral infections are the most frequent reason for medical consultations in
the world. They cause substantial illness and death every year, especially in young children …