Modified nucleotides in tRNA are critical components of the translation apparatus, but their
importance in the process of translational regulation had until recently been greatly …

Biofilms are generally defined as communities of cells involved in a self-produced
extracellular matrix adhered to a surface. In biofilms, the bacteria are less sensitive to host …

Threonylcarbamoyladenosine (t6 A) is a modified nucleoside universally conserved in t RNA
s in all three kingdoms of life. The recently discovered genes for t6 A synthesis, including tsa …

Streptococcus dysgalactiae subsp. dysgalactiae (SDSD), a Lancefield group C streptococci
(GCS), is a frequent cause of bovine mastitis. This highly prevalent disease is the costliest in …

The human oral cavity harbors approximately 1,000 microbial species, and dysbiosis of the
microflora and imbalanced microbiota-host interactions drive many oral diseases, such as …

The increasing antibiotic resistance poses a significant global health challenge, threatening
our ability to combat infectious diseases. The phenomenon of collateral sensitivity, whereby …

Background Streptococcus mutans is the primary etiological agent of human dental caries. It
can metabolize a wide variety of carbohydrates and produce large amounts of organic acids …

Green synthesized silver nanoparticles (AgNPs) are expected to have rich biomedical
applications as an alternative medicine for health care, with the bioactive compounds of …

Streptococcus mutans, with the ability of high‐rate acid production and strong biofilm
formation, is considered the predominant bacterial species in the pathogenesis of human …

A robust cell envelope is the first line of protection for an infecting pathogen when
encountering the immune defense of its host. In Gram-positive organisms, LytR-CpsA-Psr …