Compartmentalization of Gene Expression during Bacillus subtilis Spore Formation

DW Hilbert, PJ Piggot - Microbiology and molecular biology …, 2004 - Am Soc Microbiol
Gene expression in members of the family Bacillaceae becomes compartmentalized after
the distinctive, asymmetrically located sporulation division. It involves complete …

Temporal and spatial regulation in prokaryotic cell cycle progression and development

KR Ryan, L Shapiro - Annual review of biochemistry, 2003 - annualreviews.org
▪ Abstract Bacteria exhibit a high degree of intracellular organization, both in the timing of
essential processes and in the placement of the chromosome, the division site, and …

Evidence for a novel protease governing regulated intramembrane proteolysis and resistance to antimicrobial peptides in Bacillus subtilis

CD Ellermeier, R Losick - Genes & development, 2006 - genesdev.cshlp.org
Evidence is presented that the activation of the RNA polymerase σ factor σW in Bacillus
subtilis by regulated intramembrane proteolysis is governed by a novel, membrane …

Sporulation and Enterotoxin (CPE) Synthesis Are Controlled by the Sporulation-Specific Sigma Factors SigE and SigK in Clostridium perfringens

KH Harry, R Zhou, L Kroos, SB Melville - Journal of bacteriology, 2009 - Am Soc Microbiol
Clostridium perfringens is the third most frequent cause of bacterial food poisoning annually
in the United States. Ingested C. perfringens vegetative cells sporulate in the intestinal tract …

Spore cortex formation in Bacillus subtilis is regulated by accumulation of peptidoglycan precursors under the control of sigma K

P Vasudevan, A Weaver, ED Reichert… - Molecular …, 2007 - Wiley Online Library
The bacterial endospore cortex peptidoglycan is synthesized between the double
membranes of the developing forespore and is required for attainment of spore dehydration …

A branched pathway governing the activation of a developmental transcription factor by regulated intramembrane proteolysis

N Campo, DZ Rudner - Molecular cell, 2006 - cell.com
The proteolytic activation of the membrane-associated transcription factor pro-σ K is
controlled by a signal transduction pathway during sporulation in the bacterium Bacillus …

BofA protein inhibits intramembrane proteolysis of pro-σK in an intercompartmental signaling pathway during Bacillus subtilis sporulation

R Zhou, L Kroos - Proceedings of the National Academy of …, 2004 - National Acad Sciences
Bacillus subtilis is a bacterium that undergoes a developmental program of sporulation in
response to starvation. At the core of the program are σ factors, whose regulated …

Serine proteases from two cell types target different components of a complex that governs regulated intramembrane proteolysis of pro‐σK during Bacillus subtilis …

R Zhou, L Kroos - Molecular microbiology, 2005 - Wiley Online Library
Upon starvation Bacillus subtilis undergoes a developmental process involving creation of
two cell types, the mother cell and forespore. A signal in the form of a serine protease …

SpoIVB‐mediated cleavage of SpoIVFA could provide the intercellular signal to activate processing of Pro‐σK in Bacillus subtilis

TC Dong, SM Cutting - Molecular microbiology, 2003 - Wiley Online Library
SpoIVB is the critical determinant for intercompartmental signalling of pro‐σK processing
during sporulation in Bacillus subtilis. We show here that the SpoIVB serine peptidase can …

Inhibitory proteins block substrate access by occupying the active site cleft of Bacillus subtilis intramembrane protease SpoIVFB

S Olenic, L Heo, M Feig, L Kroos - Elife, 2022 - elifesciences.org
Intramembrane proteases (IPs) function in numerous signaling pathways that impact health,
but elucidating the regulation of membrane-embedded proteases is challenging. We …