Pediatric tumors are uncommon, yet are the leading cause of cancer-related death in
childhood. Tumor types, molecular characteristics, and pathogenesis are unique, often …

Hepatoblastoma (HB) is the most common malignant liver tumor that occurs during
childhood. The prognosis of children with HB is favorable when a complete surgical …

Background & Aims Hepatoblastoma (HB) is the most frequent childhood liver cancer.
Patients with aggressive tumors have limited therapeutic options; therefore, a better …

Chronic liver diseases usually developed through stepwise pathological transitions under
the persistent risk factors. The molecular changes during liver transitions are pivotal to …

Cancer is the most complex genetic disease known, with mutations implicated in more than
250 genes. However, it is still elusive which specific mutations found in human patients lead …

Objective To investigate the role of hsa_circ_0008934 in osteosarcoma and the molecular
mechanism involved in the regulation of the occurrence and development of osteosarcoma …

Breast cancer is a major global health burden with high morbidity and mortality rates.
Previous studies have reported that increased expression of ASAP1 is associated with poor …

Relapsed and metastatic hepatoblastoma represents an unmet clinical need with limited
chemotherapy treatment options. In a chemical screen, we identified volasertib as an agent …

Purpose Hepatoblastoma is the most common liver malignancy in children. In order to
advance therapy against hepatoblastoma, novel immunologic targets and biomarkers are …

Hepatoblastoma (HB) is one of the most common hepatic malignancies in the pediatric
population. HB are composed of a variety of tumors, which derived from different origins and …