Acute benzo [a] pyrene treatment causes different antioxidant response and DNA damage in liver, lung, brain, stomach and kidney

C Deng, F Dang, J Gao, H Zhao, S Qi, M Gao - Heliyon, 2018 - cell.com
Acute effects of oxidative damage induced by benzo [a] pyrene (B [a] P) on various organs
are still not clear. In this study, we investigated oxidative stress and DNA damage in liver …

Antioxidative 1, 4-dihydropyridine derivatives modulate oxidative stress and growth of human osteoblast-like cells in vitro

L Milkovic, T Vukovic, N Zarkovic, F Tatzber… - Antioxidants, 2018 - mdpi.com
Oxidative stress has been implicated in pathophysiology of different human stress-and age-
associated disorders, including osteoporosis for which antioxidants could be considered as …

Insecticidal activity and mechanism of cinnamaldehyde in C. elegans

L Lu, C Shu, L Chen, Y Yang, S Ma, K Zhu, B Shi - Fitoterapia, 2020 - Elsevier
Cinnamon is the dried bark of Cinnamomum cassia Presl, and its main component is
cinnamaldehyde (CA). Decades of synthetic pesticide use to control parasitic nematodes …

Withania somnifera leaf extract ameliorates benzo [a] pyrene-induced behavioral and neuromorphological alterations by improving brain antioxidant status in …

R Mohanty, SK Das, NR Singh, M Patri - Zebrafish, 2016 - liebertpub.com
The aquatic environment provides a sink for the environmental pollutants that have potential
to induce oxidative stress by altering neurobehavioral response of aquatic animals. Benzo …

Benzo-α-pyrene induced oxidative stress in Caenorhabditis elegans and the potential involvements of microRNA

H Wu, C Huang, FA Taki, Y Zhang, DL Dobbins, L Li… - Chemosphere, 2015 - Elsevier
In the present study oxidative stress induced by Benzo-α-pyrene (BaP) exposure and the
potential involvements of microRNA were investigated. The Caenorhabditis elegans (C …

The Nrf2‐ARE pathway is associated with Schisandrin b attenuating benzo(a)pyrene‐Induced HTR cells damages in vitro

Q Dong, H Hou, J Wu, Y Chen - Environmental toxicology, 2016 - Wiley Online Library
As is ubiquitous in the environmental sources, benzo (a) pyrene (BaP) has been reported to
induce reprotoxicity in previous studies. Toxicity to trophoblast cells may be one key factor …

Neonatal exposure to benzo [a] pyrene induces oxidative stress causing altered hippocampal cytomorphometry and behavior during early adolescence period of male …

B Patel, SK Das, S Das, L Das, M Patri - International Journal of …, 2016 - Elsevier
Environmental neurotoxicants like benzo [a] pyrene (B [a] P) have been well documented
regarding their potential to induce oxidative stress. However, neonatal exposure to B [a] P …

Testicular and epididymal toxicity induced by benzo (a) pyrene, alcohol, and their combination in Wistar rats

KP Reddy, PS Reddy - Toxicology research, 2016 - academic.oup.com
Alcoholism and cigarette smoking are pervasive problems that have been implicated in
human health. In this study, independent and combinative toxicities of alcohol and benzo (a) …

Determination of 3-OHB[a]P and (+)-anti-BPDE in Rats Blood and Brain Tissue of B[a]P Exposure by HPLC with Fluorescence Detection

XC Liu, L Qi, N Ma, G Yang, N Liu, G Chen, H Liu… - Chromatographia, 2015 - Springer
The aim of this paper was to develop an analytical method for determining the levels of the
Benzo [a] pyrene (B [a] P) metabolites, 3-hydroxybenzo (a) pyrene (3-OHB [a] P), and (+) …

Induction of oxidative stress by benzo (a) pyrene in the epididymis of Wistar rats

KP Reddy, P Madhu, PS Reddy - Toxicological & Environmental …, 2015 - Taylor & Francis
The present study was undertaken to evaluate the effect of sub-chronic exposure to benzo
(a) pyrene on the antioxidant system and histology of rat epididymal sperm. Intraperitoneal …