Recent advances in triterpenoid pathway elucidation and engineering

S Dinday, S Ghosh - Biotechnology Advances, 2023 - Elsevier
Triterpenoids are among the most assorted class of specialized metabolites found in all the
taxa of living organisms. Triterpenoids are the leading active ingredients sourced from plant …

Using Synthetic Biology to Understand the Function of Plant Specialized Metabolites

Y Bai, X Liu, IT Baldwin - Annual Review of Plant Biology, 2024 - annualreviews.org
Plant specialized metabolites (PSMs) are variably distributed across taxa, tissues, and
ecological contexts; this variability has inspired many theories about PSM function, which to …

Resolving plant development in space and time with single-cell genomics

TM Nolan, R Shahan - Current opinion in plant biology, 2023 - Elsevier
Single-cell genomics technologies are ushering in a new research era. In this review, we
summarize the benefits and current challenges of using these technologies to probe the …

Integrated transcriptomic and metabolomic analysis reveals the molecular basis of tissue-specific accumulation of bioactive steroidal alkaloids in Fritillaria …

H Liao, H Quan, B Huang, H Ji, T Zhang, J Chen… - Phytochemistry, 2023 - Elsevier
Fritillaria unibracteata is an endangered medicinal plant whose bulb has been used as a
Chinese herb to suppress cough, asthma and excessive phlegm for centuries. Steroidal …

Nitrogen sensing and regulatory networks: it's about time and space

CM Shanks, K Rothkegel, MD Brooks, CY Cheng… - The Plant …, 2024 - academic.oup.com
A plant's response to external and internal nitrogen signals/status relies on sensing and
signaling mechanisms that operate across spatial and temporal dimensions. From a …

Populus MYC2 orchestrates root transcriptional reprogramming of defence pathway to impair Laccaria bicolor ectomycorrhizal development

JE Marqués‐Gálvez, G Pandharikar, V Basso… - New …, 2024 - Wiley Online Library
The jasmonic acid (JA) signalling pathway plays an important role in the establishment of
the ectomycorrhizal symbiosis. The Laccaria bicolor effector MiSSP7 stabilizes JA …

Understanding metabolic diversification in plants: branchpoints in the evolution of specialized metabolism

W Ji, A Osbourn, Z Liu - Philosophical Transactions B, 2024 - royalsocietypublishing.org
Plants are chemical engineers par excellence. Collectively they make a vast array of
structurally diverse specialized metabolites. The raw materials for building new pathways …

Decoding resilience: ecology, regulation, and evolution of biosynthetic gene clusters

GL Cawood, J Ton - Trends in Plant Science, 2024 - cell.com
Secondary metabolism is crucial for plant survival and can generate chemistry with
nutritional, therapeutic, and industrial value. Biosynthetic genes of selected secondary …

Cell type-specific control and post-translational regulation of specialized metabolism: opening new avenues for plant metabolic engineering

N Ntelkis, A Goossens, K Šola - Current Opinion in Plant Biology, 2024 - Elsevier
Although plant metabolic engineering enables the sustainable production of valuable
metabolites with many applications, we still lack a good understanding of many multi …

[HTML][HTML] Identification of a bZIP transcription factor PpTGA3 regulating polyphyllin biosynthesis in Paris polyphylla

XL Pu, LY Zhang, JY Zhang, X Ye, L Lin, DR Wu… - Industrial Crops and …, 2025 - Elsevier
The biosynthesis and transcriptional regulation of active ingredients in medicinal plants
have garnered significant research attention. In this study, we focused on the transcriptional …