Of mice and men: the coronavirus MHV and mouse models as a translational approach to understand SARS-CoV-2

RW Koerner, M Majjouti, MAA Alcazar, E Mahabir - Viruses, 2020 - mdpi.com
The fatal acute respiratory coronavirus disease 2019 (COVID-19) is caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2). Since COVID-19 was declared a …

Elucidating the neuropathologic mechanisms of SARS-CoV-2 infection

M Pacheco-Herrero, LO Soto-Rojas… - Frontiers in …, 2021 - frontiersin.org
The current pandemic caused by the new severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) has become a public health emergency. To date, March 1, 2021, coronavirus …

A review on SARS-CoV-2-induced neuroinflammation, neurodevelopmental complications, and recent updates on the vaccine development

M Karnik, NM Beeraka, CA Uthaiah, SM Nataraj… - Molecular …, 2021 - Springer
Abstract Coronavirus disease 2019 (COVID-19) is a devastating viral infection caused by
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The incidence and …

Optic nerve and macular optical coherence tomography in recovered COVID-19 patients

B Burgos-Blasco, N Güemes-Villahoz… - European Journal …, 2022 - journals.sagepub.com
Purpose: To investigate the peripapillary retinal nerve fiber layer thickness (RNFLT),
macular RNFLT, ganglion cell layer (GCL), and inner plexiform layer (IPL) thickness in …

Potential of SARS-CoV-2 to cause CNS infection: biologic fundamental and clinical experience

J Huang, M Zheng, X Tang, Y Chen, A Tong… - Frontiers in …, 2020 - frontiersin.org
SARS-CoV-2 is a novel coronavirus leading to serious respiratory disease and is spreading
around the world at a raging speed. Recently there is emerging speculations that the central …

Experimental models for the study of central nervous system infection by SARS-CoV-2

I Sanclemente-Alaman, L Moreno-Jiménez… - Frontiers in …, 2020 - frontiersin.org
Introduction The response to the SARS-CoV-2 coronavirus epidemic requires increased
research efforts to expand our knowledge of the disease. Questions related to infection rates …

Pathology of coronavirus infections: A review of lesions in animals in the one-health perspective

V Zappulli, S Ferro, F Bonsembiante, G Brocca… - Animals, 2020 - mdpi.com
Simple Summary Coronaviruses are worldwide distributed RNA-viruses affecting several
species, causing a broad spectrum of diseases with a zoonotic potential and the ability to …

[HTML][HTML] Azadirachta indica A. Juss bark extract and its Nimbin isomers restrict β-coronaviral infection and replication

L Sarkar, L Oko, S Gupta, AN Bubak, B Das, P Gupta… - Virology, 2022 - Elsevier
Emerging mutations in the SARS-CoV-2 genome pose a challenge for vaccine development
and antiviral therapy. The antiviral efficacy of Azadirachta indica bark extract (NBE) was …

Ifit2 restricts murine coronavirus spread to the spinal cord white matter and its associated myelin pathology

M Sharma, D Chakravarty, A Hussain… - Journal of …, 2023 - Am Soc Microbiol
Interferon-induced protein with tetratricopeptide repeats 2, Ifit2, is critical in restricting
neurotropic murine-β-coronavirus, RSA59 infection. RSA59 intracranial injection of Ifit2 …

Matrine treatment reduces retinal ganglion cell apoptosis in experimental optic neuritis

J Kang, S Liu, Y Song, Y Chu, M Wang, Y Shi… - Scientific reports, 2021 - nature.com
Inflammatory demyelination and axonal injury of the optic nerve are hallmarks of optic
neuritis (ON), which often occurs in multiple sclerosis and is a major cause of visual …