Primers are arguably the single most critical components of any PCR assay, as their
properties control the exquisite specificity and sensitivity that make this method uniquely …

Poorly executed and inadequately reported molecular measurement methods are amongst
the causes underlying the lack of reproducibility of much biomedical research. Although …

Digital PCR (dPCR) has developed considerably since the publication of the Minimum
Information for Publication of Digital PCR Experiments (dMIQE) guidelines in 2013, with …

Parkinson's disease (PD) is a slowly progressing neurodegenerative disorder that affects
approximately seven million patients worldwide. Despite intensive research, the molecular …

The quantitative polymerase chain reaction (qPCR) is fundamental to molecular biology. It is
not just a laboratory technique, qPCR is a bridge between research and clinical practice. Its …

There is increasing concern about the reliability of biomedical research, with recent articles
suggesting that up to 85% of research funding is wasted. This article argues that an …

Although molecular testing, and RT-qPCR in particular, has been an indispensable
component in the scientific armoury targeting SARS-CoV-2, there are numerous falsehoods …

Qualitative and quantitative PCR-based tests are widely used in both diagnostics and
research to assess the prevalence of disease-causing pathogens in veterinary medicine …

Background: Recent research indicates that long non-coding RNAs (lncRNA) represent a
new family of RNAs that is of fundamental importance for controlling transcription and …

Scientific conferences fulfil many roles, but one of the most important ones is that they help
shape the direction in which a scientific discipline grows by promoting person-to-person …