Tendinopathy is a condition characterized by persistent tendon pain, structural damage, and
compromised functionality. Presently, the treatment for tendinopathy remains a formidable …

Background Fibrosis is often associated with aberrant repair mechanisms that ultimately
lead to organ failure. In the lung, idiopathic pulmonary fibrosis (IPF) is a fatal form of …

Idiopathic pulmonary fibrosis (IPF) is characterized by accumulation of myofibroblasts
(MYFs) and extracellular matrix components, which leads to severe distortion and scarring of …

Idiopathic pulmonary fibrosis is a progressive and lethal interstitial lung disease with an
unclear etiology and limited treatment options. Fatty acid synthase (FASN) plays various …

Alveologenesis is the final stage of lung development in which the internal surface area of
the lung is increased to facilitate efficient gas exchange in the mature organism. The first …

Alveolar regeneration requires the coordinated engagement of epithelial stem cells and
mesenchymal niche cells to restore the intricate alveolar architecture of the lung. The current …

Tissue inhibitor of metalloproteinases-1 (TIMP-1) is a physiologic inhibitor of the matrix
metalloproteinases (MMPs), but little is known about the role of TIMP-1 in regulating the …

Probiotics are essential in the body's nutrients, improving the ratio of meat to meat, immune
response, and preventing diseases. In this study, RNA-sequencing (RNA-seq) was used to …

Increased circulating tissue inhibitor of metalloproteinases‐1 (TIMP‐1) levels have been
observed in patients with acute lung injury (ALI). However, the sex‐specific regulation of …

Systemic sclerosis (SSc) is a complex autoimmune disease characterized by fibrosis,
vascular abnormalities, and immune dysfunction, with no definitive cure. Patients with …