Heart failure (HF) imposes significant economic and public health burdens upon modern
society. It is known that disturbances in neurohormonal status play an important role in the …

Precision Medicine (PM) is an innovative approach that, by relying on large populations'
datasets, patients' genetics and characteristics, and advanced technologies, aims at …

Cardiovascular diseases are the leading causes of death in the world. The limited
regenerative capacity of adult cardiomyocytes is the major barrier for heart regeneration …

Aims Mechanochemical signalling drives organogenesis and is highly conserved in
mammal evolution. Regaining recovery in myocardial jeopardy by inducing principles …

The irreversible loss of functional cardiomyocytes (CMs) after myocardial infarction (MI)
represents one major barrier to heart regeneration and functional recovery. The combination …

Various stem cells have been explored for the purpose of cardiac repair. However, any
individual stem cell population has not been considered as the ideal source. Recently …

Background The aim of the present study was to investigate the role of microRNA (miRNA)
let-7a in down-regulation of β 1-adrenoceptors (β 1-AR) and elucidate the underlying …

Background miR-23b overexpression can promote cardiomyocyte apoptosis and reduce cell
growth under hypoxic conditions, suggesting that miR-23b acts as a biomarker for ST …

Background The poor viability of transplanted mesenchymal stem cells (MSCs) hampers
their therapeutic efficacy for ischemic heart disease. Micro RNA s are involved in regulation …

Introduction: Cardiac remodelling is a complex pathogenetic pathway involving genome
expression, molecular, cellular, and interstitial changes that cause changes in size, shape …