Basement membranes: cell scaffoldings and signaling platforms

PD Yurchenco - Cold Spring Harbor perspectives in …, 2011 - cshperspectives.cshlp.org
Basement membranes are widely distributed extracellular matrices that coat the basal
aspect of epithelial and endothelial cells and surround muscle, fat, and Schwann cells …

Transmembrane crosstalk between the extracellular matrix and the cytoskeleton

B Geiger, A Bershadsky, R Pankov… - Nature reviews Molecular …, 2001 - nature.com
Integrin-mediated cell adhesions provide dynamic, bidirectional links between the
extracellular matrix and the cytoskeleton. Besides having central roles in cell migration and …

Morphogenesis and development of human telencephalic organoids in the absence and presence of exogenous extracellular matrix

C Martins‐Costa, VA Pham, J Sidhaye… - The EMBO …, 2023 - embopress.org
The establishment and maintenance of apical‐basal polarity is a fundamental step in brain
development, instructing the organization of neural progenitor cells (NPCs) and the …

Collagen IV is essential for basement membrane stability but dispensable for initiation of its assembly during early development

E Pöschl, U Schlötzer-Schrehardt, B Brachvogel… - 2004 - journals.biologists.com
Basement membranes are specialized extracellular matrices consisting of tissue-specific
organizations of multiple matrix molecules and serve as structural barriers as well as …

Form and function: the laminin family of heterotrimers

H Colognato, PD Yurchenco - Developmental dynamics: an …, 2000 - Wiley Online Library
The laminins are a family of glycoproteins that provide an integral part of the structural
scaffolding of basement membranes in almost every animal tissue. Each laminin is a …

Intercellular movement of the putative transcription factor SHR in root patterning

K Nakajima, G Sena, T Nawy, PN Benfey - Nature, 2001 - nature.com
Positional information is pivotal for establishing developmental patterning in plants,,, but little
is known about the underlying signalling mechanisms. The Arabidopsis root radial pattern is …

Expression and function of laminins in the embryonic and mature vasculature

R Hallmann, N Horn, M Selg, O Wendler… - Physiological …, 2005 - journals.physiology.org
Endothelial cells of the blood and lymphatic vasculature are polarized cells with luminal
surfaces specialized to interact with inflammatory cells upon the appropriate stimulation; …

Post-translational disruption of dystroglycan–ligand interactions in congenital muscular dystrophies

DE Michele, R Barresi, M Kanagawa, F Saito, RD Cohn… - Nature, 2002 - nature.com
Muscle–eye–brain disease (MEB) and Fukuyama congenital muscular dystrophy (FCMD)
are congenital muscular dystrophies with associated, similar brain malformations,. The …

Dystroglycan: from biosynthesis to pathogenesis of human disease

R Barresi, KP Campbell - Journal of cell science, 2006 - journals.biologists.com
α-and β-dystroglycan constitute a membrane-spanning complex that connects the
extracellular matrix to the cytoskeleton. Although a structural role for dystroglycan had been …

Endothelial cell laminin isoforms, laminins 8 and 10, play decisive roles in T cell recruitment across the blood–brain barrier in experimental autoimmune …

M Sixt, B Engelhardt, F Pausch, R Hallmann… - The Journal of cell …, 2001 - rupress.org
An active involvement of blood–brain barrier endothelial cell basement membranes in
development of inflammatory lesions in the central nervous system (CNS) has not been …