Cell entry and release of quasi-enveloped human hepatitis viruses

A Das, EE Rivera-Serrano, X Yin, CM Walker… - Nature Reviews …, 2023 - nature.com
Infectious hepatitis type A and type E are caused by phylogenetically distinct single-
stranded, positive-sense RNA viruses that were once considered to be non-enveloped …

Hepatitis A virus infection

P Van Damme, RM Pintó, Z Feng, F Cui… - Nature Reviews …, 2023 - nature.com
Hepatitis A is a vaccine-preventable infection caused by the hepatitis A virus (HAV). Over
150 million new infections of hepatitis A occur annually. HAV causes an acute inflammatory …

Genetic glycoengineering in mammalian cells

Y Narimatsu, C Büll, YH Chen, HH Wandall… - Journal of Biological …, 2021 - ASBMB
Advances in nuclease-based gene-editing technologies have enabled precise, stable, and
systematic genetic engineering of glycosylation capacities in mammalian cells, opening up a …

The global trends and regional differences in incidence and mortality of hepatitis A from 1990 to 2019 and implications for its prevention

G Cao, W Jing, J Liu, M Liu - Hepatology international, 2021 - Springer
Background and purpose Despite decades of improved sanitation and hygiene measures
and vaccine introduction, hepatitis A has been spread through numerous outbreaks globally …

Hepatoviruses promote very-long-chain fatty acid and sphingolipid synthesis for viral RNA replication and quasi-enveloped virus release

T Shiota, Z Li, GY Chen, KL McKnight, T Shirasaki… - Science …, 2023 - science.org
Virus-induced changes in host lipid metabolism are an important but poorly understood
aspect of viral pathogenesis. By combining nontargeted lipidomics analyses of infected cells …

[HTML][HTML] Intestinal virome and therapeutic potential of bacteriophages in liver disease

CL Hsu, Y Duan, DE Fouts, B Schnabl - Journal of hepatology, 2021 - Elsevier
Humans harbour a large quantity of microbes in the intestinal tract and have evolved
symbiotic relationships with many of them. However, several specific bacterial pathobionts …

The ZCCHC14/TENT4 complex is required for hepatitis A virus RNA synthesis

Y Li, I Misumi, T Shiota, L Sun… - Proceedings of the …, 2022 - National Acad Sciences
Despite excellent vaccines, resurgent outbreaks of hepatitis A have caused thousands of
hospitalizations and hundreds of deaths within the United States in recent years. There is no …

Pathogenicity and virulence of hepatitis A virus

RM Pintó, FJ Pérez-Rodríguez, MI Costafreda… - Virulence, 2021 - Taylor & Francis
Hepatitis A is an acute infection of the liver, which is mostly asymptomatic in children and
increases the severity with age. Although in most patients the infection resolves completely …

Viral cell-to-cell spread: Conventional and non-conventional ways

N Cifuentes-Munoz, F El Najjar, RE Dutch - Advances in virus research, 2020 - Elsevier
A critical step in the life cycle of a virus is spread to a new target cell, which generally
involves the release of new viral particles from the infected cell which can then initiate …

Glucosylceramide is essential for Heartland and Dabie bandavirus glycoprotein-induced membrane fusion

T Xia, X Wu, E Hong, K Jung, CJ Lai, MJ Kwak… - PLoS …, 2023 - journals.plos.org
Due to climate changes, there has been a large expansion of emerging tick-borne zoonotic
viruses, including Heartland bandavirus (HRTV) and Dabie bandavirus (DBV). As etiologic …