Virus-assisted directed evolution of biomolecules
D Jewel, Q Pham, A Chatterjee - Current Opinion in Chemical Biology, 2023 - Elsevier
Directed evolution is a powerful technique that uses principles of natural evolution to enable
the development of biomolecules with novel functions. However, the slow pace of natural …
the development of biomolecules with novel functions. However, the slow pace of natural …
Establishing a synthetic orthogonal replication system enables accelerated evolution in E. coli
The evolution of new function in living organisms is slow and fundamentally limited by their
critical mutation rate. Here, we established a stable orthogonal replication system in …
critical mutation rate. Here, we established a stable orthogonal replication system in …
Orthogonal RNA replication enables directed evolution and Darwinian adaptation in mammalian cells
Directed evolution in mammalian cells offers a powerful approach for advancing synthetic
biology applications. However, existing mammalian-based directed evolution methods face …
biology applications. However, existing mammalian-based directed evolution methods face …
Evolverator: An engineered in cellulo yeast system to drive rapid continuous evolution of proteins
In vivo continuous directed evolution generates genetic diversity and selects a target
phenotype to generate proteins with desired functionality. However, in current systems, the …
phenotype to generate proteins with desired functionality. However, in current systems, the …
Detectable episodic positive selection in the virion strand A-strain maize streak virus genes may have a role in its host adaptation
KA Oyeniran, MO Tenibiaje - 2024 - researchsquare.com
Maize streak virus (MSV) has only three genes: cp encoding the coat protein, mp encoding
the movement protein and rep/repA encoding two distinct replication associated proteins …
the movement protein and rep/repA encoding two distinct replication associated proteins …