[HTML][HTML] Membrane Antigen Targeting in Acute Myeloid Leukemia Using Antibodies or CAR-T Cells

U Testa, G Castelli, E Pelosi - Cancers, 2024 - mdpi.com
This review explores the emerging area of the therapeutic use of antibodies and chimeric
antigen receptor (CAR)-T cells for the treatment of acute myeloid leukemia (AML). Through a …

Regulatory T-cells: The Face-off of the Immune Balance

M Singer, AM Elsayed, MI Husseiny - Frontiers in Bioscience …, 2024 - escholarship.org
Regulatory T-cells (Tregs) play a crucial role in maintaining immune homeostasis, ensuring
a balanced immune response. Tregs primarily operate in an antigen-specific fashion …

IFN-γ and CD38 in AML: a T-cell engagement made in heaven?

AJ Lamble, RE Rau - Blood, 2024 - ashpublications.org
Survival rates in newly diagnosed AML have plateaued over the last several decades.
Survival in the setting of relapsed disease remains dismal, making AML a disease that …