The use of bacterial cells as agents of medical therapy has a long history. Research that was
ignited over a century ago with the accidental infection of cancer patients has matured into a …

Bacterial therapies possess many unique mechanisms for treating cancer that are
unachievable with standard methods. Bacteria can specifically target tumours, actively …

It was already clinically apparent 150 years ago that bacterial therapy could alleviate
diseases. Recently, a burgeoning number of researchers have been using bacterial …

There is growing interest in the role of microorganisms in human health and disease, with
evidence showing that new types of biotherapy using engineered bacterial therapeutics …

Metastasis accounts for 90% of cancer-related deaths and, currently, there are no effective
clinical therapies to block the metastatic cascade. A need to develop novel therapies …

Abstract In this White Paper, we discuss the current state of microbial cancer therapy. This
paper resulted from a meeting ('Microbial Based Cancer Therapy') at the US National …

Bacteria are associated with the human body and colonize the gut, skin, and mucous
membranes. These associations can be either symbiotic or pathogenic. In either case …

Bacterial therapy, which presents a smart platform for delivering and producing therapeutic
agents, as monotherapy or in combination with other therapeutic modes, has provided a …

Engineered bacterial therapies that target the tumor immune landscape offer a new class of
cancer immunotherapy. Salmonella enterica and Listeria monocytogenes are two species of …

Bacteria act as pro-or anti-tumorigenic agents. Whole bacteria or cytotoxic or immunogenic
peptides carried by them exert potent anti-tumor effects in the experimental models of …