Restoration of metal homeostasis: A potential strategy against neurodegenerative diseases

YY Zhang, XS Li, KD Ren, J Peng, XJ Luo - Ageing Research Reviews, 2023 - Elsevier
Metal homeostasis is critical to normal neurophysiological activity. Metal ions are involved in
the development, metabolism, redox and neurotransmitter transmission of the central …

Microbiota-accessible boron-containing compounds in complex regional pain syndrome

CE Biţă, IR Scorei, AF Vreju, AE Muşetescu… - Medicina, 2023 - mdpi.com
The microbiota–gut–brain axis has garnered increasing attention in recent years for its role
in various health conditions, including neuroinflammatory disorders like complex regional …

Interrupted Homolytic Substitution Enables Organoboron Compounds to Inhibit Radical Chain Reactions Rather than Initiate Them

Z Wu, R Vlaming, M Donohoe… - Journal of the American …, 2023 - ACS Publications
The reactions of organoboranes with peroxyl radicals are key to their use as radical initiators
for a vast array of radical chain reactions, particularly at low temperatures where high …

Boron Compounds Mitigate 2, 3, 7, 8-Tetrachlorodibenzo-p-dioxin-Induced Toxicity in Human Peripheral Blood Mononuclear Cells

ME Arslan, C Baba, OO Tozlu - Toxics, 2024 - mdpi.com
2, 3, 7, 8-Tetrachlorodibenzo-p-dioxin (TCDD) stands as one of the most potent halogenated
polycyclic hydrocarbons, known to inflict substantial cytotoxic effects on both animal and …

Effect of coating with chitosan enriched with different borates on the shelf life of fish fillet

G Alak, A Ucar, V Parlak, H Turkez… - Journal of the …, 2023 - Wiley Online Library
BACKGROUND In this study, the effects of biofilm coatings obtained by immobilization of
different borates–namely borax (BX), colemanite (COL), and ulexite (UX)–with chitosan (Ch) …

[HTML][HTML] In vitro evaluation of the cytotoxic and genotoxic effects of Al and Mn in ambient concentrations detected in groundwater intended for human consumption

LFV Francisco, D da Silva Baldivia… - Ecotoxicology and …, 2023 - Elsevier
Environmental exposure to metals can induce cytotoxic and genotoxic effects in cells and
affect the health of the exposed population. To investigate the effects of aluminum (Al) and …

Neuroprotective properties of borax against aluminum hydroxide-induced neurotoxicity: Possible role of Nrf-2/BDNF/AChE pathways in fish brain

G Alak, H Turkez, A Ucar, AC Yeltekin, FB Ozgeris… - Brain research, 2023 - Elsevier
The current study was designed to assess the possible neuroprotective effect of borax (BX)
against the toxicity of aluminum hydroxide [AH, Al (OH) 3] on brain of rainbow trout …

Isoimperatorin therapeutic effect against aluminum induced neurotoxicity in albino mice

P Rajendran, D Althumairy, M Bani-Ismail… - Frontiers in …, 2023 - frontiersin.org
Background: Although aluminum (Al) is not biologically crucial to the human body, classical
studies have demonstrated that excessive human exposure to Al can induce oxidative …

Oxidative, Genotoxic and Cytotoxic Damage Potential of Novel Borenium and Borinium Compounds

SB Oguzkan, H Turkez, HI Ugras, A Tatar… - Inorganics, 2023 - mdpi.com
In this study, the biological properties of novel borenium and borinium compounds in terms
of their oxidative, genotoxic, and cytotoxic effects were assessed on cultured human …

Boron: An Intriguing Factor in Retarding Alzheimer's Progression

A Das, V Rajput, D Chowdhury, R Choudhary… - Neurochemistry …, 2024 - Elsevier
Alzheimer's disease (AD) is a neurodegenerative disorder that is the fifth most common
cause of mortality worldwide and the second most common cause of death in developed …