This review explores sustainable strategies for enhancing the solubility of poorly water-
soluble pharmaceutical active ingredients (PAIs), focusing on hydrotropy and co-solvency …

Mixed solvency concept in reducing surfactant concentration of self‑emulsifying drug delivery
systems of candesartan cilexetil Page 1 Asian Journal of Pharmaceutics - April-June 2013 83 …

A number of trained models based on the Jouyban-Acree model were proposed for
prediction of naproxen (NAP) solubility in the cosolvency systems. The predictive cosolvency …

The term “hydrotropy” is generally used to enhance the solubility of the drug agents by
mixing a sufficient amount of alkali metal salts. Nevertheless, this term describes nonmicelle …

Based on the large number of experiments on solubilization of poorly water-soluble drugs,
The auther is of the opinion that hydrotropy is another type of cosolvency and all water …

In present research work a new simple, specific, precise, accurate, robust and economical
UV-Spectrophotometric method for simultaneous estimation of ofloxacin and ornidazole in …

Objectives The main aim of the research was to analyze an economical and eco-friendly
approach to improve the solubility of norfloxacin. The current analysis was to utilize the …

The pollution and toxicity caused by most of the organic solvents is a big challenge. The
researchers are doing much work to give ecofriendly solutions for this challenge …

Poor solubility is one ofthe most difficult problems ofmaximum drugs. Mixed hydrotropy is
one of the advanced method, in which aqueous solubility of poorly water-soluble drugs is …