The organic cation transporters (OCTs) OCT1, OCT2, OCT3, novel OCT (OCTN) 1, OCTN2,
multidrug and toxin exclusion (MATE) 1, and MATE kidney-specific 2 are polyspecific …

The SLC22 family contains 13 functionally characterized human plasma membrane proteins
each with 12 predicted α-helical transmembrane domains. The family comprises organic …

Organic cation transporters (OCTs) of the solute carrier family (SLC) 22 and multidrug and
toxin extrusion (MATE) transporters of the SLC47 family have been identified as uptake and …

Our understanding of the mechanisms behind inter‐and intra‐patient variability in drug
response is inadequate. Advances in the cytochrome P450 drug metabolizing enzyme field …

Mycotoxins frequently contaminate food and feed materials, posing a threat to human and
animal health. Fusarium species produce important mycotoxins with regard to their …

Abstract Aflatoxin B1 (AFB1), a common dietary contaminant, is a major risk factor of
hepatocellular carcinoma (HCC). Early onset of HCC in some countries in Africa and South …

Patulin, a known mycotoxin, is considered a significant contaminant in apples, apple-derived
products and feeds. This study investigated the genotoxic effects of patulin in multiple …

Mycotoxins are metabolites produced by fungi. The widespread contamination of food and
feed by mycotoxins is a global food safety problem and a serious threat to people's health …

The development of cardiovascular diseases is often attributable to loss of endothelial
functions of the vascular tissue or to decreased contractile function of the heart muscle …

Changes in the uptake of many drugs by the target cells may dramatically affect the
pharmacological response. Thus, downregulation of SLC22A1, which encodes the organic …