The unique architecture of the mammalian lung is required for adaptation to air breathing at
birth and thereafter. Understanding the cellular and molecular mechanisms controlling its …

Retinoic acid (RA) is a key molecular player in embryogenesis and adult tissue
homeostasis. In embryo development, RA plays a crucial role in the formation of different …

Despite therapeutic advancement, pulmonary disease still remains a major cause of
morbidity and mortality around the world. Opportunities to study human lung disease either …

We observed two unrelated consanguineous families with malformation syndromes sharing
anophthalmia and distinct eyebrows as common signs, but differing for alveolar capillary …

The lungs are generated by branching morphogenesis as a result of reciprocal signalling
interactions between the epithelium and mesenchyme during development. Mutations that …

The purpose of this study was to investigate the human nasal epithelial cell line RPMI 2650
regarding its usefulness as in vitro model for drug permeation studies. Particularly, the …

Although alveolar wall thinning has been attributed to apoptosis of interstitial lung
lipofibroblasts (LFs), the underlying molecular mechanism (s) remains unknown. Although …

The history of physiologic cellular–molecular interrelationships can be traced all the way
back to the unicellular state by following the pathway formed by lipids ubiquitously …

Induction of morphogenesis by competent lung progenitor cells in a 3D environment is a
central goal of pulmonary tissue engineering, yet little is known about the …

Lung morphogenesis is a highly orchestrated process beginning with the appearance of
lung buds on approximately embryonic day 9.5 in the mouse. Endodermally derived …