The integration of whole genome sequencing (WGS) into all aspects of modern medicine
represents the next step in the evolution of healthcare. Using this technology, scientists and …

Hypertrophic cardiomyopathy (HCM) is the most common inherited cardiac disease
associated with morbidity and mortality at any age. As studies in recent decades have …

Motivation: Genome-wide association studies (GWAS) have identified genetic variants,
usually single-nucleotide polymorphisms (SNPs), associated with human traits, including …

Macrobrachium nipponense is a commercially important freshwater species of prawn that is
widely distributed across Asian countries. In order to investigate the molecular mechanisms …

Background: The pathogenesis of congenital heart disease (CHD) has not been fully
elucidated, and this study considers the interaction between inheritance and the …

Purpose of Review GWAS, as a largely correlational analysis, requires in vitro or in vivo
validation. Zebrafish (Danio rerio) have many advantages for studying the genetics of …

Sekvenciranje cijeloga genoma (eng. Whole genome sequencing–WGS) postaje sve
zastupljeniji genetički dijagnostički test u svakodnevnoj kliničkoj praksi. Inicijativa za …

High-throughput chromatin conformation capture technologies, such as Hi-C and Micro-C,
have enabled genome-wide view of chromatin spatial organization. Most recently, Hi-C …

Harnessing the power of single-cell genomics technologies, single-cell Hi-C (scHi-C) and its
derived technologies provide powerful tools to measure spatial proximity between regulatory …

HiChIP enables cost-effective and high-resolution profiling of regulatory and structural loops.
To leverage the increasing number of publicly available HiChIP datasets from diverse cell …