Type 1 diabetes mellitus (T1D) is a chronic disease characterized by an autoimmune
destruction of insulin-producing β-pancreatic cells. Although many advances have been …

Diabetes mellitus (DM) is one of the most prevalent metabolic disorders. In order to replace
the function of the destroyed pancreatic beta cells in diabetes, islet transplantation is the …

Modeling amyotrophic lateral sclerosis (ALS) with human induced pluripotent stem cells
(iPSCs) aims to reenact embryogenesis, maturation and aging of spinal motor neurons …

Targeted differentiation of pluripotent stem (PS) cells into myotubes enables in vitro disease
modeling of skeletal muscle diseases. Although various protocols achieve myogenic …

Abstract Background Pancreatic progenitors (PPs) co-expressing the two transcription
factors (TFs) PDX1 and NKX6. 1 are recognized as the indispensable precursors of …

Desirable cells for human cell therapy would be ones that can be generated by simple
isolation and culture techniques using a donor sample obtained by non-invasive methods …

Tooth derived stem cells or dental stem cells are categorized according to the location from
which they are isolated and represent a promising source of cells for regenerative medicine …

Introduction: Islet transplantation can treat the most severe cases of type 1 diabetes but it
currently requires deceased donor pancreata as an islet source and chronic …

Large volume of urine is continuously released into the environment by both humans and
animals, and impacts negatively on the environment and ultimately on humans and animals' …

The loss of functional β cells leads to development of diabetes. Several studies have shown
that β cells are specified through several stages of progenitors during pancreas …