Cerebral small vessel disease (cSVD) is a major cause of stroke and dementia. This review
summarizes recent developments in advanced neuroimaging of cSVD with a focus on …

Background Cerebral small vessel disease (cSVD) is a major contributing factor to ischemic
stroke and dementia. However, the vascular pathologies of cSVD remain inconclusive. The …

BACKGROUND: Cerebrovascular reactivity (CVR) is inversely related to white matter
hyperintensity severity, a marker of cerebral small vessel disease (SVD). Less is known …

Background Cerebrovascular reactivity (CVR) is a measure of the change in cerebral blood
flow (CBF) in response to a vasoactive challenge. It is a useful indicator of the brain's …

Ultra-high field functional magnetic resonance imaging (fMRI) offers the spatial resolution to
measure neuronal activity at the scale of cortical layers. However, cortical depth dependent …

Background and Objectives Factors associated with cerebral small vessel disease (SVD)
progression, including incident infarcts, are unclear. We aimed to determine the frequency of …

Introduction: Cerebrovascular reactivity (CVR) measurements using blood oxygen level
dependent (BOLD) magnetic resonance imaging (MRI) are commonly used to assess the …

Cerebral small vessel disease (cSVD), a common cause of stroke and dementia, is
traditionally considered the small vessel equivalent of large artery occlusion or rupture that …

In this work, we demonstrate a data-driven approach for estimating cerebrovascular
reactivity (CVR) amplitude and lag from breathhold (BH) fMRI data alone. Our approach …

Breath-holding (BH) tasks during functional magnetic resonance imaging (fMRI) acquisitions
are gaining popularity for non-invasive mapping of carbon-dioxide (CO2) driven …