RA Scarfone, SM Pena, KA Russell, DH Betts… - BMC veterinary …, 2020 - Springer
Induced pluripotent stem cells (iPSCs) are undifferentiated stem cells characterized by the ability to differentiate into any cell type in the body. iPSCs are a relatively new and rapidly …
JV Conrad, S Meyer, PS Ramesh, JA Neira… - Stem Cell Reports, 2023 - cell.com
Sus scrofa domesticus (pig) has served as a superb large mammalian model for biomedical studies because of its comparable physiology and organ size to humans. The derivation of …
M Katayama, T Fukuda, T Kaneko, Y Nakagawa… - Communications …, 2022 - nature.com
The number of endangered avian-related species increase in Japan recently. The application of new technologies, such as induced pluripotent stem cells (iPSCs), may …
J Xu, L Yu, J Guo, J Xiang, Z Zheng, D Gao… - Stem Cell Research & …, 2019 - Springer
Background Pigs have emerged as one of the most popular large animal models in biomedical research, which in many cases is considered as a superior choice over rodent …
Y Ma, T Yu, Y Cai, H Wang - Cell death discovery, 2018 - nature.com
Derivation of bona fide porcine pluripotent stem cells is still a critical issue because porcine embryonic stem cells (ESCs) are not available yet, and most of the culture conditions to …
Culture conditions regulate the process of pluripotency acquisition and self-renewal. This study aimed to analyse the influence of the in vitro environment on the induction of porcine …
The lysine demethylases KDM5B and KDM5C are highly, but transiently, expressed in porcine embryos around the genome activation stage. Attenuation of KDM5B and KDM5C …
H Jiao, MS Lee, A Sivapatham, EM Leiferman… - Scientific Reports, 2022 - nature.com
Miniature pigs are an ideal animal model for translational research to evaluate stem cell therapies and regenerative applications. While the derivation of induced pluripotent stem …
X Cong, SM Zhang, MW Ellis, J Luo - Stem Cells and Development, 2019 - liebertpub.com
Induced pluripotent stem cell (iPSC) technology offers a practically infinite and ethically acceptable source to obtain a variety of somatic cells. Coupled with the biotechnologies of …