Hairy cell leukemia: present and future directions

RJ Kreitman - Leukemia & lymphoma, 2019 - Taylor & Francis
Hairy cell leukemia (HCL) is an indolent B-cell malignancy, with long-term responses to
purine analogs, but with decreasing efficacy and increasing toxicity with repeated courses …

Vemurafenib plus rituximab in refractory or relapsed hairy-cell leukemia

E Tiacci, L De Carolis, E Simonetti… - … England Journal of …, 2021 - Mass Medical Soc
Background Hairy-cell leukemia (HCL) is a CD20+ indolent B-cell cancer in which a BRAF
V600E kinase–activating mutation plays a pathogenetic role. In clinical trials involving …

Moxetumomab pasudotox in heavily pre-treated patients with relapsed/refractory hairy cell leukemia (HCL): long-term follow-up from the pivotal trial

RJ Kreitman, C Dearden, PL Zinzani, J Delgado… - Journal of hematology & …, 2021 - Springer
Background Moxetumomab pasudotox is a recombinant CD22-targeting immunotoxin. Here,
we present the long-term follow-up analysis of the pivotal, multicenter, open-label trial …

Long term follow-up of a phase II study of cladribine with concurrent rituximab with hairy cell leukemia variant

D Chihara, E Arons, M Stetler-Stevenson… - Blood …, 2021 - ashpublications.org
Hairy cell leukemia variant (HCLv) responds poorly to purine analogue monotherapy.
Rituximab concurrent with cladribine (CDAR) improves response rates, but long-term …

Moxetumomab pasudotox for the treatment of relapsed and/or refractory hairy cell leukemia

I Abou Dalle, F Ravandi - Expert review of hematology, 2019 - Taylor & Francis
Introduction: Hairy cell leukemia is a rare indolent B-cell malignancy, characterized by
pancytopenia, recurrent infections, and splenomegaly. After initial therapy with purine …

Droplet digital polymerase chain reaction for the assessment of disease burden in hairy cell leukemia

A Broccoli, C Terragna, L Nanni… - Hematological …, 2022 - Wiley Online Library
BRAFV600E mutation is the pathogenic driver of hairy cell leukemia (HCL) found in the vast
majority of cases both at onset and during recurrences. The identification of the mutated …

Haarzellleukämie

T Robak, S Dietrich - Indolente Lymphome, 2023 - Springer
Die Haarzellleukämie (HCL) ist eine seltene chronische B-Zell-Neoplasie, die durch eine
ausgeprägte Splenomegalie, eine progressive Panzytopenie und eine reaktive …

Leucémie à tricholeucocytes: quelles sont les meilleures options thérapeutiques pour les patients en rechute ou réfractaires?

X Troussard, E Maitre, J Paillassa - Bulletin du Cancer, 2021 - Elsevier
Résumé La leucémie à tricholeucocytes est une hémopathie maligne rare: trois cents
nouveaux cas sont diagnostiqués chaque année en France. Le diagnostic repose sur:(1) …

[HTML][HTML] Hairy Cell Leukemia

LA Andritsos, M Anghelina, KE Johnson - mdedge-cache.beta.mdedge.com
Hairy cell leukemia (HCL) is a rare chronic lymphoproliferative disorder, with only
approximately 2000 new cases diagnosed in the United States each year. 1 It is now …

[HTML][HTML] Hospital Physician: Hematology/Oncology

A Kibirova, SJ Hall, MA Salken - 207.231.204.223
Breast cancer is the second leading cause of cancer deaths among women in the United
States, according to the SEER database. It is estimated that 1 in 8 women will be diagnosed …