Role of biomarkers for the prevention, assessment, and management of heart failure: a scientific statement from the American Heart Association
SL Chow, AS Maisel, I Anand, B Bozkurt, RA De Boer… - Circulation, 2017 - Am Heart Assoc
Background and Purpose: Natriuretic peptides have led the way as a diagnostic and
prognostic tool for the diagnosis and management of heart failure (HF). More recent …
prognostic tool for the diagnosis and management of heart failure (HF). More recent …
Computational and statistical analysis of metabolomics data
Metabolomics is the comprehensive study of small molecule metabolites in biological
systems. By assaying and analyzing thousands of metabolites in biological samples, it …
systems. By assaying and analyzing thousands of metabolites in biological samples, it …
[HTML][HTML] The human urine metabolome
S Bouatra, F Aziat, R Mandal, AC Guo, MR Wilson… - PloS one, 2013 - journals.plos.org
Urine has long been a “favored” biofluid among metabolomics researchers. It is sterile, easy-
to-obtain in large volumes, largely free from interfering proteins or lipids and chemically …
to-obtain in large volumes, largely free from interfering proteins or lipids and chemically …
Metabolic disturbances identified in plasma are associated with outcomes in patients with heart failure: diagnostic and prognostic value of metabolomics
ML Cheng, CH Wang, MS Shiao, MH Liu… - Journal of the American …, 2015 - jacc.org
Background: Identification of novel biomarkers is needed to improve the diagnosis and
prognosis of heart failure (HF). Metabolic disturbance is remarkable in patients with HF …
prognosis of heart failure (HF). Metabolic disturbance is remarkable in patients with HF …
Engineered extracellular vesicles derived from dermal fibroblasts attenuate inflammation in a murine model of acute lung injury
AI Salazar‐Puerta, MA Rincon‐Benavides… - Advanced …, 2023 - Wiley Online Library
Acute respiratory distress syndrome (ARDS) represents a significant burden to the
healthcare system, with≈ 200 000 cases diagnosed annually in the USA. ARDS patients …
healthcare system, with≈ 200 000 cases diagnosed annually in the USA. ARDS patients …
Standardizing the experimental conditions for using urine in NMR-based metabolomic studies with a particular focus on diagnostic studies: a review
The metabolic composition of human biofluids can provide important diagnostic and
prognostic information. Among the biofluids most commonly analyzed in metabolomic …
prognostic information. Among the biofluids most commonly analyzed in metabolomic …
Metabolomic fingerprint of heart failure with preserved ejection fraction
Background Heart failure (HF) with preserved ejection fraction (HFpEF) is increasingly
recognized as an important clinical entity. Preclinical studies have shown differences in the …
recognized as an important clinical entity. Preclinical studies have shown differences in the …
Gut-microbiota-metabolite axis in early renal function decline
C Barrios, M Beaumont, T Pallister, J Villar… - PloS one, 2015 - journals.plos.org
Introduction Several circulating metabolites derived from bacterial protein fermentation have
been found to be inversely associated with renal function but the timing and disease severity …
been found to be inversely associated with renal function but the timing and disease severity …
Urinary biomarkers of brain diseases
M An, Y Gao - Genomics, Proteomics and Bioinformatics, 2015 - academic.oup.com
Biomarkers are the measurable changes associated with a physiological or
pathophysiological process. Unlike blood, urine is not subject to homeostatic mechanisms …
pathophysiological process. Unlike blood, urine is not subject to homeostatic mechanisms …
Urine metabolome profiling of immune-mediated inflammatory diseases
Background Immune-mediated inflammatory diseases (IMIDs) are a group of complex and
prevalent diseases where disease diagnostic and activity monitoring is highly challenging …
prevalent diseases where disease diagnostic and activity monitoring is highly challenging …