Plasmodium falciparum malaria, an infectious disease caused by a parasitic protozoan,
claims the lives of nearly a million children each year in Africa alone and is a top public …

Malaria remains a major public health threat in tropical and subtropical regions across the
world. Even though less than 1% of malaria infections are fatal, this leads to about 430,000 …

Microbes exert a major impact on human health and disease by either promoting or
disrupting homeostasis, in the latter instance leading to the development of infectious …

Bilirubin is the end product of heme catabolism formed during a process that involves
oxidation-reduction reactions and conserves iron body stores. Unconjugated …

Coevolution of humans and malaria parasites has generated an intricate balance between
the immune system of the host and virulence factors of the parasite, equilibrating maximal …

Benign ethnic neutropenia (BEN) is one of the most common causes of chronic neutropenia
seen in individuals of African, Middle Eastern and West Indian descent, affecting many …

The pathogenesis of infectious diseases depends on the interaction of host and pathogen. In
Plasmodium falciparum malaria, host and parasite processes can be assessed by dual RNA …

Plasmodium falciparum malaria kills over 500,000 children every year and has been a
scourge of humans for millennia. Owing to the co-evolution of humans and P. falciparum …

It is not known why people are more susceptible to bacterial infections such as nontyphoid
Salmonella during and after a malaria infection, but in mice, malarial hemolysis impairs …

Disease tolerance is a defense strategy that limits the fitness costs of infection irrespectively
of pathogen burden. While restricting iron (Fe) availability to pathogens is perceived as a …