Endometriosis is a chronic systemic disease: clinical challenges and novel innovations

HS Taylor, AM Kotlyar, VA Flores - The Lancet, 2021 - thelancet.com
Endometriosis is a common disease affecting 5–10% of women of reproductive age globally.
However, despite its prevalence, diagnosis is typically delayed by years, misdiagnosis is …

Progesterone and estrogen signaling in the endometrium: what goes wrong in endometriosis?

RM Marquardt, TH Kim, JH Shin, JW Jeong - International journal of …, 2019 - mdpi.com
In the healthy endometrium, progesterone and estrogen signaling coordinate in a tightly
regulated, dynamic interplay to drive a normal menstrual cycle and promote an embryo …

Progesterone resistance in endometriosis: origins, consequences and interventions

BG Patel, M Rudnicki, J Yu, Y Shu… - Acta obstetricia et …, 2017 - Wiley Online Library
Endometriosis is a common cause of pelvic pain and affects up to 10% of women of
reproductive age. Aberrant progesterone signaling in the endometrium plays a significant …

Consensus on current management of endometriosis

NP Johnson, L Hummelshoj… - Human …, 2013 - academic.oup.com
STUDY QUESTION Is there a global consensus on the management of endometriosis that
considers the views of women with endometriosis? SUMMARY ANSWER It was possible to …

[PDF][PDF] Dysmenorrhea, endometriosis and chronic pelvic pain in adolescents

A Sachedina, N Todd - Journal of clinical research in pediatric …, 2020 - jag.journalagent.com
Most adolescents will experience discomfort during menstruation. Due to normalization of
dysmenorrhea, there is delay to diagnosis and treatment. Non-steroidal anti-inflammatories …

[HTML][HTML] Reevaluating response and failure of medical treatment of endometriosis: a systematic review

CM Becker, WT Gattrell, K Gude, SS Singh - Fertility and sterility, 2017 - Elsevier
Objective To assess patient response rates to medical therapies used to treat endometriosis-
associated pain. Design A systematic review with the use of Medline and Embase. Setting …

Systematic review of endometriosis pain assessment: how to choose a scale?

N Bourdel, J Alves, G Pickering, I Ramilo… - Human reproduction …, 2015 - academic.oup.com
BACKGROUND Numerous studies concerning endometriosis and pain have been reported.
However, there is no consensus on the best method to evaluate pain in endometriosis and …

Current and emerging treatment options for endometriosis

S Ferrero, G Evangelisti, F Barra - Expert opinion on …, 2018 - Taylor & Francis
Introduction: Pharmacotherapy has a pivotal role in the management of endometriosis with
long-term treatments balancing clinical efficacy (control of pain symptoms and prevention of …

[HTML][HTML] Progestin-only pills may be a better first-line treatment for endometriosis than combined estrogen-progestin contraceptive pills

RF Casper - Fertility and sterility, 2017 - Elsevier
For decades, combined estrogen-progestin oral contraceptive pills (OCPs) have been the
first-line treatment for menstrual and pelvic pain associated with endometriosis without any …

Age-related infertility

NM Crawford, AZ Steiner - Obstetrics and Gynecology Clinics, 2015 - obgyn.theclinics.com
Societal shifts, triggered by a greater focus on education and careers, have resulted in a
trend toward delayed childbearing in American women. Between 1970 and 2002, the …