Obligately intracytosolic rickettsiae that cycle between arthropod and vertebrate hosts cause
human diseases with a spectrum of severity, primarily by targeting microvascular endothelial …

Hematophagous arthropods are responsible for the transmission of a variety of pathogens
that cause disease in humans and animals. Ticks of the Ixodes ricinus complex are vectors …

Human infections with arthropod-borne Rickettsia species remain a major global health
issue, causing significant morbidity and mortality. Epidemic typhus due to Rickettsia …

Mediterranean spotted fever (MSF) is an emerging tick-borne rickettsiosis of the spotted
fever group (SFG), endemic in the Mediterranean basin. By virtue of technological …

Rickettsiae are obligate intracellular bacteria that can cause life-threatening illnesses and
are among the oldest known vector-borne pathogens. Members of this genus are …

Pathogenic bacteria secrete protein effectors to hijack host machinery and remodel their
infectious niche. Rickettsia spp. are obligate intracellular bacteria that can cause life …

Bacterial infection is a highly complex biological process involving a dynamic interaction
between the invading microorganism and the host. Specifically, intracellular pathogens …

Rickettsiae are responsible for some of the most devastating human infections. A high
infectivity and severe illness after inhalation make some rickettsiae bioterrorism threats. We …

Several bacterial pathogens, including Listeria monocytogenes, Shigella flexneri and
Rickettsia spp., have evolved mechanisms to actively spread within human tissues …

Anaplasma phagocytophilum is the tick-transmitted obligate intracellular bacterium that
causes human granulocytic anaplasmosis (HGA). A. phagocytophilum binding to sialyl …