Self-therapeutic nanomaterials: Applications in biology and medicine

J Seaberg, JR Clegg, R Bhattacharya, P Mukherjee - Materials Today, 2023 - Elsevier
Over past decades, nanotechnology has contributed to the biomedical field in areas
including detection, diagnosis, and drug delivery via opto-electronic properties or …

Gold nanostructure-mediated delivery of anticancer agents: Biomedical applications, reversing drug resistance, and stimuli-responsive nanocarriers

M Entezari, GGY Abad, B Sedghi, R Ettehadi… - Environmental …, 2023 - Elsevier
The application of nanoarchitectures in cancer therapy seems to be beneficial for the
delivery of antitumor drugs. In recent years, attempts have been made to reverse drug …

MAD2L2, a key regulator in ovarian cancer and promoting tumor progression

K Xu, X Zheng, H Shi, J Ou, H Ding - Scientific Reports, 2024 - nature.com
Ovarian cancer (OVCA), a prevalent gynecological malignancy, ranks as the fourth most
common cancer among women. Mitotic Arrest Deficient 2 Like 2 (MAD2L2), a chromatin …

Gold Nanoparticles Inhibit Macropinocytosis by Decreasing KRAS Activation

CK Elechalawar, G Rao, SK Gulla, MM Patel… - ACS …, 2023 - ACS Publications
The RAS-transformed cells utilize macropinocytosis to acquire amino acids to support their
uncontrolled growth. However, targeting RAS to inhibit macropinocytosis remains a …

Interrogation of the Tumor Microenvironment by Nanoparticles

P Panja, U Manne, V Awasthy, R Bhattacharya… - Cancer Letters, 2025 - Elsevier
The tumor microenvironment (TME) plays a pivotal role in cancer progression by fostering
intricate multicellular crosstalk among cancer cells, stromal cells, and immune cells. This …

Evolving landscape of detection and targeting miRNA/epigenetics for therapeutic strategies in ovarian cancer

AD Bhowmik, P Shaw, MSG Pillai, G Rao, SKD Dwivedi - Cancer Letters, 2025 - Elsevier
Ovarian cancer (OC) accounts for the highest mortality rates among all gynecologic
malignancies. The high mortality of OC is often associated with delayed detection …

Ultrasound-assisted green synthesis of gold nanoparticles mediated by Staghorn sumac for the treatment of lung cancer: Introducing a novel chemotherapeutic drug

B Zhang, X Sun, J Tang - Inorganic Chemistry Communications, 2024 - Elsevier
The present research has dealt with setting up single-distributed gold nanoparticles by
employing the sedimentary excerpt extract of Staghorn sumac under ultrasonic conditions …

[HTML][HTML] The biomedical application of inorganic metal nanoparticles in aging and aging-associated diseases

Y Meng, J Zhang, Y Liu, Y Zhu, H Lv, F Xia… - Journal of Advanced …, 2024 - Elsevier
Aging and aging-associated diseases (AAD), including neurodegenerative disease, cancer,
cardiovascular diseases, and diabetes, are inevitable process. With the gradual …

Integrated Multiomics Reveals Silencing of has_circ_0006646 Promotes TRIM21‐Mediated NCL Ubiquitination to Inhibit Hepatocellular Carcinoma Metastasis

X Hu, G Chen, Y Huang, Q Cheng, J Zhuo… - Advanced …, 2024 - Wiley Online Library
Recent studies suggest that circular RNA (circRNA)‐mediated post‐translational
modification of RNA‐binding proteins (RBP) plays a pivotal role in metastasis of …

Autophagy-mediated nanomaterials for tumor therapy

Z Liao, X Liu, D Fan, X Sun, Z Zhang, P Wu - Frontiers in Oncology, 2023 - frontiersin.org
Autophagy is a lysosomal self-degradation pathway that plays an important protective role in
maintaining intracellular environment. Deregulation of autophagy is related to several …