The human brain undergoes a prolonged period of cortical development that spans multiple
decades. During childhood and adolescence, cortical development progresses from lower …

Abstract Systems neuroscience approaches with a focus on large-scale brain organization
and network analysis are advancing foundational knowledge of how cognitive control …

Cognitive and behavioural flexibility permit the appropriate adjustment of thoughts and
behaviours in response to changing environmental demands. Brain mechanisms enabling …

Executive control is a complex high-level cognitive function that relies on distributed brain
circuitry. We propose that the anterior insular cortex plays an under-appreciated role in …

Psychiatric disorders are highly prevalent, often devastating diseases that negatively impact
the lives of millions of people worldwide. Although their etiological and diagnostic …

How individual differences in brain network organization track behavioral variability is a
fundamental question in systems neuroscience. Recent work suggests that resting-state and …

The view that substance addiction is a brain disease, although widely accepted in the
neuroscience community, has become subject to acerbic criticism in recent years. These …

Despite a longstanding and widespread influence of the diagnostic approach to mental ill
health, there is an emerging and growing consensus that such psychiatric nosologies may …

Abstract Concepts of cognitive control (CC) and executive function (EF) are defined in terms
of their relationships with goal-directed behavior versus habits and controlled versus …

Importance Mental health professionals typically encounter patients at 1 point in patients'
lives. This cross-sectional window understandably fosters focus on the current presenting …