Tendon injuries are a global health problem that affects millions of people annually. The
properties of tendons make their natural rehabilitation a very complex and long-lasting …

Growth factors (GFs) are signaling molecules that direct cell development by providing
biochemical cues for stem cell proliferation, migration, and differentiation. GFs play a key …

Tendon injuries cause prolonged disability and never recover completely. Current
mechanistic understanding of tendon regeneration is limited. Here, we use single-cell …

Tissue engineering is a promising approach to repair tendon and muscle when natural
healing fails. Biohybrid constructs obtained after cells' seeding and culture in dedicated …

Coupling between angiogenesis and osteogenesis has an important role in both normal
bone injury repair and successful application of tissue‐engineered bone for bone defect …

Angiogenesis is crucial to facilitate tendon healing, such as delivering oxygen and nutrients,
removing waste products, and controlling immune responses. Vascular endothelial growth …

Tendon injuries suffer from a slow healing, often ending up in fibrovascular scar formation,
leading to inferior mechanical properties and even re-rupture upon resumption of daily work …

Tendon adhesion formation describes the development of fibrotic tissue between the tendon
and its surrounding tissues, which commonly occurs as a reaction to injury or surgery. Its …

Extracellular matrix (ECM) hydrogels obtained from decellularized tissues are promising
biocompatible materials for tissue regeneration. These biomaterials may provide important …

A major problem after tendon laceration is the low mechanical strength of the repaired
tissue. One viable strategy for improving the functional and biomechanical properties of …