The spread, treatment, and prevention of HIV-1: evolution of a global pandemic

MS Cohen, N Hellmann, JA Levy… - The Journal of …, 2008 - Am Soc Clin Investig
The most up-to-date estimates demonstrate very heterogeneous spread of HIV-1, and more
than 30 million people are now living with HIV-1 infection, most of them in sub-Saharan …

Non‐nucleoside reverse transcriptase inhibitors (NNRTIs): past, present, and future

E De Clercq - Chemistry & biodiversity, 2004 - Wiley Online Library
Non‐nucleoside reverse transcriptase (RT) inhibitors (NNRTIs) have become an inherent
ingredient of the drug combination schemes that are currently used in the treatment of …

Intrapartum and neonatal single-dose nevirapine compared with zidovudine for prevention of mother-to-child transmission of HIV-1 in Kampala, Uganda: 18-month …

JB Jackson, P Musoke, T Fleming, LA Guay… - The Lancet, 2003 - thelancet.com
Background In 1999, we reported safety and efficacy data for short-course nevirapine from a
Ugandan perinatal HIV-1 prevention trial when 496 babies were followed up to age 14–16 …

[HTML][HTML] Single-dose perinatal nevirapine plus standard zidovudine to prevent mother-to-child transmission of HIV-1 in Thailand

M Lallemant, G Jourdain, S Le Coeur… - … England Journal of …, 2004 - Mass Medical Soc
Background Although zidovudine prophylaxis decreases the rate of transmission of the
human immunodeficiency virus (HIV) type 1 substantially, a large number of infants still …

[图书][B] Prevention and promotion in mental health

World Health Organization - 2002 - apps.who.int
The World Health Organization (WHO) defines health as “a state of complete physical,
mental and social well-being and not merely the absence of disease or infirmity”. Thus, in …

Efficacy of three short-course regimens of zidovudine and lamivudine in preventing early and late transmission of HIV-1 from mother to child in Tanzania, South Africa …

Petra Study Team - The Lancet, 2002 - Elsevier
BACKGROUND: Large reductions in transmission of HIV-1 from mother to child have been
achieved in more-developed countries due to the use of antiretrovirals. Short-course …

Antiretroviral drug resistance testing in adults infected with human immunodeficiency virus type 1: 2003 recommendations of an International AIDS Society-USA Panel

MS Hirsch, F Brun-Vézinet, B Clotet… - Clinical Infectious …, 2003 - academic.oup.com
New information about the benefits and limitations of testing for resistance to human
immunodeficiency virus (HIV) type 1 (HIV-1) drugs has emerged. The International AIDS …

Lamivudine-zidovudine combination for prevention of maternal-infant transmission of HIV-1

L Mandelbrot, A Landreau-Mascaro, C Rekacewicz… - Jama, 2001 - jamanetwork.com
ContextZidovudine reduces maternal-infant transmission of human immunodeficiency virus
1 (HIV-1) infection by two thirds. Combination antiretroviral therapies are potentially more …

Adherence–resistance relationships for protease and non-nucleoside reverse transcriptase inhibitors explained by virological fitness

DR Bangsberg, EP Acosta, R Gupta, D Guzman… - Aids, 2006 - journals.lww.com
Objective: To compare the prevalence of resistance by adherence level in patients treated
with non-nucleoside reverse transcriptase inhibitors (NNRTI) or protease inhibitors (PI). Also …

Selection and fading of resistance mutations in women and infants receiving nevirapine to prevent HIV-1 vertical transmission (HIVNET 012)

SH Eshleman, M Mracna, LA Guay, M Deseyve… - Aids, 2001 - journals.lww.com
Objective To examine the emergence and fading of NVP resistance (NVP R) mutations in
HIV-1-infected Ugandan women and infants who received single dose NVP to prevent HIV-1 …